Evidence map›Paper›PMID 36662412›Full record

ArticleNeurotoxicity research2023

Neuroprotective and Immunomodulatory Effects of Probiotics in a Rat Model of Parkinson's Disease.

Irving Parra, Isabel Martínez, Lizbeth Vásquez-Celaya, Jose L Gongora-Alfaro, Yousef Tizabi, Liliana Mendieta

Abstract read
PubMed Publisher
In one paragraph

Article in Neurotoxicity research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Irving ParraLaboratorio de Neuroquímica, Facultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, San Claudio CU, 14 Sur Y AvCol. San Manuel, 72570, Puebla, Mexico.
Isabel MartínezLaboratorio de Neuroquímica, Facultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, San Claudio CU, 14 Sur Y AvCol. San Manuel, 72570, Puebla, Mexico.
Lizbeth Vásquez-CelayaLaboratorio de Neurofisiología, Centro de Investigaciones Regionales "Dr, Hideyo Noguchi", Universidad Autónoma de Yucatán, Yucatán, Mexico.
Jose L Gongora-AlfaroLaboratorio de Neurofisiología, Centro de Investigaciones Regionales "Dr, Hideyo Noguchi", Universidad Autónoma de Yucatán, Yucatán, Mexico.
Yousef TizabiDepartment of Pharmacology, Howard University College of Medicine, Washington, DC, USA.
Liliana MendietaLaboratorio de Neuroquímica, Facultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, San Claudio CU, 14 Sur Y AvCol. San Manuel, 72570, Puebla, Mexico. liliana.martinezmen@correo.buap.mx.ORCID http://orcid.org/0000-0001-6049-2770
Benemérita Universidad Autónoma de Puebla · MXAutonomous University of Yucatán · MXHoward University · US

Funding

Consejo Nacional de Ciencia y Tecnología a CONACYT-scholarship (1024175)Consejo Nacional de Ciencia y Tecnología JLGA-256878PRODEP-SEP 511-6/2020-2912
6 · The paper itself

Abstract

It is now well recognized that a bidirectional relationship between gut microbiota and the brain, referred to as the gut-brain axis, plays a prominent role in maintaining homeostasis and that a disruption in this axis can result in neuroinflammatory response and neurological disorders such as Parkinson's disease (PD). The protective action of probiotics such as Bifidobacterium animalis ssp. lactis Bb12 and Lactobacillus rhamnosus GG in various animal models of PD has been reported. Therefore, in this study, we used an inflammatory model of PD to assess the effects of a combination of these two probiotics (Microbiot

Indexed as

Bifidobacterium animalisLacticaseibacillus rhamnosusParkinson DiseaseProbioticsAnimalsLipopolysaccharidesMaleRatsRats, WistarLipopolysaccharidesBifidobacterium animalisHemiparkinsonismInflammationLactobacillus rhamnosusLipopolysaccharideProbiotics

Identifiers

PMID36662412
OpenAlexW4317566608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.