Evidence map›Paper›PMID 36662207›Full record

ArticleMarine drugs2022

Marine Sponge and Octocoral-Associated Bacteria Show Versatile Secondary Metabolite Biosynthesis Potential and Antimicrobial Activities against Human Pathogens.

João F Almeida, Matilde Marques, Vanessa Oliveira, Conceição Egas, Dalila Mil-Homens, Romeu Viana, Daniel F R Cleary, Yusheng M Huang, Arsénio M Fialho, Miguel C Teixeira and 3 more

Abstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Genome sequence of the marine alphaproteobacteriumMicrobiology resource announcements · 2024
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

João F AlmeidaiBB-Institute for Bioengineering and Biosciences and i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.ORCID 0000-0002-8305-5095
Matilde MarquesiBB-Institute for Bioengineering and Biosciences and i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.ORCID 0000-0001-9443-0893
Vanessa OliveiraDepartment of Biology and Centre for Environmental and Marine Studies (CESAM), University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-4223-0851
Conceição EgasCenter for Neuroscience and Cell Biology (CNC), Rua Larga-Faculdade de Medicina, University of Coimbra, 3004-504 Coimbra, Portugal.
Dalila Mil-HomensiBB-Institute for Bioengineering and Biosciences and i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.ORCID 0000-0002-9727-3579
Romeu VianaiBB-Institute for Bioengineering and Biosciences and i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.
Daniel F R ClearyDepartment of Biology and Centre for Environmental and Marine Studies (CESAM), University of Aveiro, 3810-193 Aveiro, Portugal.
Yusheng M HuangDepartment of Marine Recreation, National Penghu University of Science and Technology, Magong City 880-011, Taiwan.ORCID 0000-0002-6495-2620
Arsénio M FialhoiBB-Institute for Bioengineering and Biosciences and i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.ORCID 0000-0002-8066-5787
Miguel C TeixeiraiBB-Institute for Bioengineering and Biosciences and i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.ORCID 0000-0002-5676-6174
Newton C M GomesDepartment of Biology and Centre for Environmental and Marine Studies (CESAM), University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-1934-0091
Rodrigo CostaiBB-Institute for Bioengineering and Biosciences and i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.ORCID 0000-0002-5932-4101
Tina Keller-CostaiBB-Institute for Bioengineering and Biosciences and i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.ORCID 0000-0003-3702-9192

Funding

Direção-Geral de Política do Mar (Fundo Azul program) FA_05_2017_032Fundação para a Ciência e Tecnologia PTDC/BIA-MIC/6473/2014 - POCI-01-0145-FEDER-419 016531Fundação para a Ciência e Tecnologia UIDB/04565/2020; UIDP/04565/2020; LA/P/0140/2020; UIDP/50017/2020; UIDB/50017/2020; LA/P/0094/2020
6 · The paper itself

Abstract

Marine microbiomes are prolific sources of bioactive natural products of potential pharmaceutical value. This study inspected two culture collections comprising 919 host-associated marine bacteria belonging to 55 genera and several thus-far unclassified lineages to identify isolates with potentially rich secondary metabolism and antimicrobial activities. Seventy representative isolates had their genomes mined for secondary metabolite biosynthetic gene clusters (SM-BGCs) and were screened for antimicrobial activities against four pathogenic bacteria and five pathogenic

Indexed as

AnthozoaAnti-Infective AgentsPoriferaAnimalsBacteriaCandidaHumansMultigene FamilyPhylogenySecondary MetabolismAnti-Infective Agentsbioprospectionbiosynthetic gene clustersblue biotechnologyculture collectionsgenomicsmarine bacteria

Identifiers

PMID36662207
PMCPMC9860996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.