Evidence map›Paper›PMID 36662175›Full record

ArticleMarine drugs2022

Bioassay-Guided Fractionation Leads to the Detection of Cholic Acid Generated by the Rare

Fazlin Pheiffer, Yannik K-H Schneider, Espen Holst Hansen, Jeanette Hammer Andersen, Johan Isaksson, Tobias Busche, Christian Rückert, Jörn Kalinowski, Leonardo van Zyl, Marla Trindade

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Fazlin PheifferInstitute for Microbial Biotechnology and Metagenomics (IMBM), Department of Biotechnology, University of the Western Cape, Robert Sobukwe Road, Bellville, Cape Town 7535, South Africa.ORCID 0000-0001-7133-1147
Yannik K-H SchneiderMarbio, UiT-The Arctic University of Norway, N-9037 Tromsø, Norway.ORCID 0000-0001-6506-1187
Espen Holst HansenMarbio, UiT-The Arctic University of Norway, N-9037 Tromsø, Norway.ORCID 0000-0003-0354-986X
Jeanette Hammer AndersenMarbio, UiT-The Arctic University of Norway, N-9037 Tromsø, Norway.ORCID 0000-0002-6059-060X
Johan IsakssonDepartment of Chemistry, UiT -The Arctic University of Norway, Breivika, N-9037 Tromsø, Norway.ORCID 0000-0001-6287-7594
Tobias BuscheInstitute for Innovation Transfer GmbH (IIT), Universitätsstraße 25, 33615 Bielefeld, Germany.
Christian RückertInstitute for Innovation Transfer GmbH (IIT), Universitätsstraße 25, 33615 Bielefeld, Germany.ORCID 0000-0002-9722-4435
Jörn KalinowskiInstitute for Innovation Transfer GmbH (IIT), Universitätsstraße 25, 33615 Bielefeld, Germany.ORCID 0000-0002-9052-1998
Leonardo van ZylInstitute for Microbial Biotechnology and Metagenomics (IMBM), Department of Biotechnology, University of the Western Cape, Robert Sobukwe Road, Bellville, Cape Town 7535, South Africa.ORCID 0000-0001-9364-8671
Marla TrindadeInstitute for Microbial Biotechnology and Metagenomics (IMBM), Department of Biotechnology, University of the Western Cape, Robert Sobukwe Road, Bellville, Cape Town 7535, South Africa.ORCID 0000-0002-2478-0270
UiT The Arctic University of Norway · NOUniversity of the Western Cape · ZA

Funding

National Research Foundation UID87326
6 · The paper itself

Abstract

Bacterial symbionts of marine invertebrates are rich sources of novel, pharmaceutically relevant natural products that could become leads in combatting multidrug-resistant pathogens and treating disease. In this study, the bioactive potential of the marine invertebrate symbiont

Indexed as

Anti-Bacterial AgentsCholic AcidDNA, BacterialHumansPhylogenySequence Analysis, DNAAnti-Bacterial AgentsCholic AcidDNA, Bacterialbacterial natural productsbile acidbioactivitycholic acidgenome mininghomoserine lactone acylaseThalassomonas

Identifiers

PMID36662175
PMCPMC9860883
OpenAlexW4313466075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.