ArticleEuropean heart journal. Cardiovascular Imaging2023
Pulmonary transit time of cardiovascular magnetic resonance perfusion scans for quantification of cardiopulmonary haemodynamics.
Article in European heart journal. Cardiovascular Imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Hemodynamic Modeling and Phase-Adjustable Reconstruction of Hyperpolarized CardiacMagnetic resonance in medicine · 2026Article
- Feasibility of quantitative pulmonary function imaging in real-world cardiovascular magnetic resonance.The international journal of cardiovascular imaging · 2026Article
- Cardiopulmonary transit time measured on dynamic rubidium cardiac PET/CT is a predictor for pulmonary hypertension.EJNMMI research · 2026Article
- Prognostic value of cardiac magnetic resonance pulmonary transit time and myocardial strain across different stages of ST-elevation myocardial infarction.European journal of radiology open · 2026Article
- Left Atrial Time-to-Peak From Time-Resolved MR Angiography as a Noninvasive Indicator of Left Atrial Pressure Before Catheter Ablation of Atrial Fibrillation.Korean journal of radiology · 2026Article
- Pulmonary Transit Time Can Be Accurately Quantified From Non-Arterial Input Function Series in First-Pass Cardiac Perfusion MRI.Magnetic resonance in medicine · 2026Article
- Article
- Hepatic and Pulmonary Vasoactive Response Triggered by Potentially Hazardous Chemicals After Passing Through the Gut Mucosa.Diagnostics (Basel, Switzerland) · 2025Article
- Prognostic value of novel cardiovascular magnetic resonance transit times beyond the pulmonary circulation in patients with ventricular dysfunction.European radiology · 2025Article
- A new noninvasive evaluation method of pulmonary thromboembolism in rabbits-pulmonary transit time.Cardiovascular ultrasound · 2025Article
- Imaging of Congestion in Cardio-renal Syndrome.Current heart failure reports · 2025Review
- Pulmonary regional blood flow: validation of low-dose two-volume dynamic CT perfusion imaging in a swine model.European radiology experimental · 2025Article
- Quantitative analysis of abdominal aortic blood flow byAnnals of nuclear medicine · 2024Article
- Noninvasive Assessment of Cardiopulmonary Hemodynamics Using Cardiovascular Magnetic Resonance Pulmonary Transit Time.International journal of biomedical imaging · 2024Article
- Association of pulmonary transit time by cardiac magnetic resonance with heart failure hospitalization in a large prospective cohort with diverse cardiac conditions.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsPulmonary transit time (PTT) is the time blood takes to pass from the right ventricle to the left ventricle via pulmonary circulation. We aimed to quantify PTT in routine cardiovascular magnetic resonance imaging perfusion sequences. PTT may help in the diagnostic assessment and characterization of patients with unclear dyspnoea or heart failure (HF). METHODS AND
resultsWe evaluated routine stress perfusion cardiovascular magnetic resonance scans in 352 patients, including an assessment of PTT. Eighty-six of these patients also had simultaneous quantification of N-terminal pro-brain natriuretic peptide (NTproBNP). NT-proBNP is an established blood biomarker for quantifying ventricular filling pressure in patients with presumed HF. Manually assessed PTT demonstrated low inter-rater variability with a correlation between raters >0.98. PTT was obtained automatically and correctly in 266 patients using artificial intelligence. The median PTT of 182 patients with both left and right ventricular ejection fraction >50% amounted to 6.8 s (Pulmonary transit time: 5.9-7.9 s). PTT was significantly higher in patients with reduced left ventricular ejection fraction (<40%; P < 0.001) and right ventricular ejection fraction (<40%; P < 0.0001). The area under the receiver operating characteristics curve (AUC) of PTT for exclusion of HF (NT-proBNP <125 ng/L) was 0.73 (P < 0.001) with a specificity of 77% and sensitivity of 70%. The AUC of PTT for the inclusion of HF (NT-proBNP >600 ng/L) was 0.70 (P < 0.001) with a specificity of 78% and sensitivity of 61%.
conclusionPTT as an easily, even automatically obtainable and robust non-invasive biomarker of haemodynamics might help in the evaluation of patients with dyspnoea and HF.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.