Evidence map›Paper›PMID 36662091›Full record

ArticleJournal of functional biomaterials2023

A Novel Hydrophilic, Antibacterial Chitosan-Based Coating Prepared by Ultrasonic Atomization Assisted LbL Assembly Technique.

Xiaoyu Wang, Yuyang Zhou, Melissa Johnson, Cameron Milne, Sigen A, Yening Li, Wenxin Wang, Nan Zhang, Qian Xu

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaoyu WangCharles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.
Yuyang ZhouCentre of Micro/Nano Manufacturing Technology (MNMT-Dublin), School of Mechanical and Materials Engineering, University College Dublin, D04 KW52 Dublin, Ireland.ORCID 0000-0003-3808-5778
Melissa JohnsonCharles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.ORCID 0000-0002-6346-0309
Cameron MilneCharles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.
Sigen ACharles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.
Yening LiCentre of Micro/Nano Manufacturing Technology (MNMT-Dublin), School of Mechanical and Materials Engineering, University College Dublin, D04 KW52 Dublin, Ireland.
Wenxin WangCharles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.ORCID 0000-0002-5053-0611
Nan ZhangCentre of Micro/Nano Manufacturing Technology (MNMT-Dublin), School of Mechanical and Materials Engineering, University College Dublin, D04 KW52 Dublin, Ireland.ORCID 0000-0001-7849-3974
Qian XuCharles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the potential applicability of chitosan (CTS), we prepared aldehyde chitosan (CTS-CHO) with chitosan and sodium periodate via oxidation reaction and then a chitosan-based hydrophilic and antibacterial coating on the surface of poly (lactic acid) (PLA) film was developed and characterized. The oxidation degree was determined by Elemental analyser to be 12.53%, and a Fourier transform infrared spectroscopy was used to characterize the structure of CTS-CHO. It was evident that CTS-CHO is a biocompatible coating biomaterial with more than 80% cell viability obtained through the Live/Dead staining assay and the alamarBlue assay. The hydrophilic and antibacterial CTS-CHO coating on the PLA surface was prepared by ultrasonic atomization assisted LbL assembly technique due to Schiff's base reaction within and between layers. The CTS-CHO coating had better hydrophilicity and transparency, a more definite industrialization potential, and higher antibacterial activity at experimental concentrations than the CTS coating. All of the results demonstrated that the ultrasonic atomization-assisted LbL assembly CTS-CHO coating is a promising alternative for improving hydrophilicity and antibacterial activity on the PLA surface. The functional groups of CTS-CHO could react with active components with amino groups via dynamic Schiff's base reaction and provide the opportunity to create a drug releasing surface for biomedical applications.

Indexed as

antibacterialchitosancoatinghydrophilicPLA

Identifiers

PMID36662091
PMCPMC9863527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.