Evidence map›Paper›PMID 36662067›Full record

ReviewJournal of functional biomaterials2022

Nanoscale Topical Pharmacotherapy in Management of Psoriasis: Contemporary Research and Scope.

Mohammad Zaki Ahmad, Abdul Aleem Mohammed, Mohammed S Algahtani, Awanish Mishra, Javed Ahmad

Abstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammad Zaki AhmadDepartment of Pharmaceutics, College of Pharmacy, Najran University, Najran 11001, Saudi Arabia.ORCID 0000-0003-2979-8776
Abdul Aleem MohammedDepartment of Pharmaceutics, College of Pharmacy, Najran University, Najran 11001, Saudi Arabia.ORCID 0000-0003-2601-7962
Mohammed S AlgahtaniDepartment of Pharmaceutics, College of Pharmacy, Najran University, Najran 11001, Saudi Arabia.ORCID 0000-0003-0339-153X
Awanish MishraDepartment of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati 781101, Assam, India.ORCID 0000-0001-7863-5581
Javed AhmadDepartment of Pharmaceutics, College of Pharmacy, Najran University, Najran 11001, Saudi Arabia.ORCID 0000-0002-7025-751X

Funding

Deanship of Scientific Research at Najran University, Saudi Arabia, National Research Priorities funding program grant code (NU/NRP/MRC/11/5)
6 · The paper itself

Abstract

Psoriasis is a typical dermal condition that has been anticipated since prehistoric times when it was mistakenly implicit in being a variant of leprosy. It is an atypical organ-specific autoimmune disorder, which is triggered by the activation of T-cells and/or B-cells. Until now, the pathophysiology of this disease is not completely explicated and still, many research investigations are ongoing. Different approaches have been investigated to treat this dreadful skin disease using various anti-psoriatic drugs of different modes of action through smart drug-delivery systems. Nevertheless, there is no ideal therapy for a complete cure of psoriasis owing to the dearth of an ideal drug-delivery system for anti-psoriatic drugs. The conventional pharmacotherapy approaches for the treatment of psoriasis demand various classes of anti-psoriatic drugs with optimum benefit/risk ratio and insignificant untoward effects. The advancement in nanoscale drug delivery had a great impact on the establishment of a nanomedicine-based therapy for better management of psoriasis in recent times. Nanodrug carriers are exploited to design and develop nanomedicine-based therapy for psoriasis. It has a promising future in the improvement of the therapeutic efficacy of conventional anti-psoriatic drugs. The present manuscript aims to discuss the pathophysiology, conventional pharmacotherapy, and contemporary research in the area of nanoscale topical drug delivery systems for better management of psoriasis including the significance of targeted pharmacotherapy in psoriasis.

Indexed as

nanomedicinepathophysiologypsoriasistargeted pharmacotherapytopical delivery

Identifiers

PMID36662067
PMCPMC9867016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.