Evidence map›Paper›PMID 36662052›Full record

ReviewJournal of functional biomaterials2022

Wool Keratin Nanofibers for Bioinspired and Sustainable Use in Biomedical Field.

Diego Omar Sanchez Ramirez, Claudia Vineis, Iriczalli Cruz-Maya, Cinzia Tonetti, Vincenzo Guarino, Alessio Varesano

Open access · goldAbstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Diego Omar Sanchez RamirezCNR-STIIMA (National Research Council-Institute of Intelligent Industrial Technologies and Systems for Advanced Manufacturing), Corso Giuseppe Pella 16, 13900 Biella, Italy.ORCID 0000-0002-8569-5600
Claudia VineisCNR-STIIMA (National Research Council-Institute of Intelligent Industrial Technologies and Systems for Advanced Manufacturing), Corso Giuseppe Pella 16, 13900 Biella, Italy.ORCID 0000-0003-4670-5586
Iriczalli Cruz-MayaCNR-IPCB (National Research Council-Institute for Polymers, Composites and Biomaterials), Mostra, d'Oltremare, Pad. 20, V.le J.F. Kennedy 54, 80125 Napoli, Italy.ORCID 0000-0001-6366-3002
Cinzia TonettiCNR-STIIMA (National Research Council-Institute of Intelligent Industrial Technologies and Systems for Advanced Manufacturing), Corso Giuseppe Pella 16, 13900 Biella, Italy.ORCID 0000-0002-8451-7159
Vincenzo GuarinoCNR-IPCB (National Research Council-Institute for Polymers, Composites and Biomaterials), Mostra, d'Oltremare, Pad. 20, V.le J.F. Kennedy 54, 80125 Napoli, Italy.ORCID 0000-0003-1546-3721
Alessio VaresanoCNR-STIIMA (National Research Council-Institute of Intelligent Industrial Technologies and Systems for Advanced Manufacturing), Corso Giuseppe Pella 16, 13900 Biella, Italy.ORCID 0000-0002-5497-4842
National Research Council · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Keratin is a biocompatible and biodegradable protein as the main component of wool and animal hair fibers. Keratin-based materials support fibroblasts and osteoblasts growth. Keratin has been extracted by sulphitolysis, a green method (no harmful chemicals) with a yield of 38-45%. Keratin has been processed into nanofibers from its solutions by electrospinning. Electrospinning is a versatile and easy-to-use technique to generate nanofibers. It is an eco-friendly and economical method for the production of randomly and uniaxially oriented polymeric nanofibers. Thanks to their high specific surface area, nanofibers have great potential in the biomedical field. Keratin nanofibers have received significant attention in biomedical applications, such as tissue engineering and cell growth scaffolds, for their biocompatibility and bio-functionality. Accordingly, we propose an extensive overview of recent studies focused on the optimization of keratinbased nanofibers, emphasizing their peculiar functions for cell interactions and the role of additive phases in blends or composite systems to particularize them as a function of specific applications (i.e., antibacterial).

Indexed as

biocompatiblebiodegradableelectrospinningnanofiberswool keratin

Identifiers

PMID36662052
PMCPMC9862208
OpenAlexW4313502665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.