Evidence map›Paper›PMID 36661851›Full record

ArticleAlcohol, clinical & experimental research2023

Alcohol use and motives for drinking across the menstrual cycle in a psychiatric outpatient sample.

Jordan C Barone, Jaclyn M Ross, Anisha Nagpal, Gabriela Guzman, Erin Berenz, Raina D Pang, Tory A Eisenlohr-Moul

Open access · hybridAbstract read
In one paragraph

Article in Alcohol, clinical & experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jordan C BaroneDepartment of Psychiatry, University of Illinois at Chicago, Illinois, Chicago, USA.ORCID 0000-0002-5999-0921
Jaclyn M RossDepartment of Psychiatry, University of Illinois at Chicago, Illinois, Chicago, USA.
Anisha NagpalDepartment of Psychiatry, University of Illinois at Chicago, Illinois, Chicago, USA.
Gabriela GuzmanDepartment of Psychiatry, University of Illinois at Chicago, Illinois, Chicago, USA.
Erin BerenzDepartment of Psychology, University of Illinois at Chicago, Illinois, Chicago, USA.
Raina D PangDepartment of Population and Public Health Sciences & Psychology, University of Southern California, California, Los Angeles, USA.
Tory A Eisenlohr-MoulDepartment of Psychiatry, University of Illinois at Chicago, Illinois, Chicago, USA.
University of Illinois Chicago · USUniversity of Southern California · US

Funding

Training in the Neuroscience of Mental HealthT32MH067631 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI RASENICK, MARK M. · 2004 to 2024
$4.8M
Cyclical Neuroactive Steroid Changes, Arousal, and Proximal Suicide Risk: An Experimental ApproachRF1MH120843 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI EISENLOHR-MOUL, TORY ANNE · 2019 to 2019
$3.1M
Alcohol Research Training in epigenetics and pathophysiology (ARTEP)T32AA026577 · NIAAA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SUBHASH C. PANDEY · 2019 to 2026
$2.7M
Ovarian Hormone Withdrawal and Suicide Risk: An Experimental ApproachR00MH109667 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI EISENLOHR-MOUL, TORY ANNE · 2018 to 2020
$747k
Ovarian Hormone Withdrawal and Suicide Risk: An Experimental ApproachK99MH109667 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI EISENLOHR-MOUL, TORY ANNE · 2016 to 2017
$164k
NIAAA NIH HHS T32 AA026577NIMH NIH HHS K99 MH109667NIMH NIH HHS R00 MH109667NIMH NIH HHS RF1 MH120843NIMH NIH HHS T32 MH067631
6 · The paper itself

Abstract

backgroundFemales who misuse alcohol experience high rates of negative physical and mental health consequences. Existing findings are inconsistent but suggest a relationship between ovarian hormones and alcohol use. We aim to clarify how alcohol use and drinking motives vary across the menstrual cycle in female psychiatric outpatients using the luteinizing hormone (LH)-confirmed cycle phase.

methodsDaily self-reports (n = 3721) were collected from 94 naturally cycling females, recruited for past-month suicidal ideation, during the baseline phase of three parent clinical trials between February 2017 and May 2022. Multilevel logistic and linear models estimated the relationship between the cycle phase (with LH-surge confirmed ovulation) and daily alcohol use or drinking motives, moderated by the weekend. Models were adjusted for age, legal drinking status, substance use disorder, and the COVID-19 pandemic, and included random effects.

resultsParticipants were generally more likely to drink in the midluteal (vs. perimenstrual) phase, but more likely to drink heavily on weekends in periovulatory and perimenstrual (vs. midluteal) phases. Social motives for drinking were significantly higher on weekends in the periovulatory, mid-follicular, and midluteal phases (vs. weekdays), but this finding was non-significant in the perimenstrual phase. Participants rated drinking to cope higher in the perimenstrual phase (vs. midluteal phase), regardless of the weekend.

conclusionIn a psychiatric sample with LH-surge-confirmed ovulation, we find an increased likelihood to drink heavily in periovulatory and perimenstrual phases on weekends. We also find that the perimenstrual phase is associated with increased drinking to cope, and relatively lower weekend social drinking. Finally, random effects across models suggest individual differences in the extent to which the cycle influences drinking. Our findings stress (1) predictable phases of increased high-risk alcohol use across the menstrual cycle, and (2) the importance of individual assessment of cyclical changes in alcohol use to predict and prevent ovulation- and menses-related surges in heavy drinking.

Indexed as

COVID-19OutpatientsAlcohol DrinkingFemaleHumansLuteinizing HormoneMenstrual CyclePandemicsLuteinizing Hormonealcohol usebinge drinkingdrinking motivesmenstrual cycleovarian hormones

Identifiers

PMID36661851
PMCPMC9975029
OpenAlexW4317542951

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.