Evidence map›Paper›PMID 36661802›Full record

ReviewGels (Basel, Switzerland)2022

Update on Chitosan-Based Hydrogels: Preparation, Characterization, and Its Antimicrobial and Antibiofilm Applications.

Kokila Thirupathi, Chaitany Jayaprakash Raorane, Vanaraj Ramkumar, Selvakumari Ulagesan, Madhappan Santhamoorthy, Vinit Raj, Gopal Shankar Krishnakumar, Thi Tuong Vy Phan, Seong-Cheol Kim

Open access · goldAbstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
8.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 109 citations in OpenAlex.

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  16. Effect of melatonin loaded chitosan hydrogel on rat spinal cord injury.Veterinary research forum : an international quarterly journal · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Kokila ThirupathiDepartment of Physics, Sri Moogambigai College of Arts and Science for Women, Palacode 636808, India.
Chaitany Jayaprakash RaoraneSchool of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Vanaraj RamkumarSchool of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Selvakumari UlagesanDivision of Fisheries Life Sciences, Pukyong National University, Nam-gu, Busan 48513, Republic of Korea.ORCID 0000-0003-1000-7647
Madhappan SanthamoorthySchool of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Vinit RajSchool of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Gopal Shankar KrishnakumarDepartment of Biotechnology, Applied Biomaterials Laboratory, PSG Institute of Advanced Studies, Coimbatore 641004, India.
Thi Tuong Vy PhanCenter for Advanced Chemistry, Institute of Research and Development, Duy Tan University, 03 Quang Trung, Hai Chau, Danang 550000, Vietnam.ORCID 0000-0002-7416-4484
Seong-Cheol KimSchool of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Yeungnam University · KRDuy Tan University · VNPSG Institute of Advanced Studies · INPukyong National University · KR

Funding

Ministry of SMEs and Startups S3060516National Re-search Foundation of Korea (NRF) funded by the Ministry of Education 2020R1I1A3052258
6 · The paper itself

Abstract

Chitosan is a prominent biopolymer in research for of its physicochemical properties and uses. Each year, the number of publications based on chitosan and its derivatives increases. Because of its comprehensive biological properties, including antibacterial, antioxidant, and tissue regeneration activities, chitosan and its derivatives can be used to prevent and treat soft tissue diseases. Furthermore, chitosan can be employed as a nanocarrier for therapeutic drug delivery. In this review, we will first discuss chitosan and chitosan-based hydrogel polymers. The structure, functionality, and physicochemical characteristics of chitosan-based hydrogels are addressed. Second, a variety of characterization approaches were used to analyze and validate the physicochemical characteristics of chitosan-based hydrogel materials. Finally, we discuss the antibacterial, antibiofilm, and antifungal uses of supramolecular chitosan-based hydrogels. This review study can be used as a base for future research into the production of various types of chitosan-based hydrogels in the antibacterial and antifungal fields.

Indexed as

antibacterial activityantibiofilmantifungal materialschitosan-based hydrogelstructural characterization

Identifiers

PMID36661802
PMCPMC9858335
OpenAlexW4313392453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.