Evidence map›Paper›PMID 36661794›Full record

ArticleGels (Basel, Switzerland)2022

Growth Factor Binding Peptides in Poly (Ethylene Glycol) Diacrylate (PEGDA)-Based Hydrogels for an Improved Healing Response of Human Dermal Fibroblasts.

Abigail J Clevenger, Andrea C Jimenez-Vergara, Erin H Tsai, Gabriel de Barros Righes, Ana M Díaz-Lasprilla, Gustavo E Ramírez-Caballero, Dany J Munoz-Pinto

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Abigail J ClevengerEngineering Science Department, Trinity University, San Antonio, TX 78212, USA.ORCID 0000-0002-1242-8130
Andrea C Jimenez-VergaraEngineering Science Department, Trinity University, San Antonio, TX 78212, USA.
Erin H TsaiChemistry Department, Trinity University, San Antonio, TX 78212, USA.
Gabriel de Barros RighesEngineering Science Department, Trinity University, San Antonio, TX 78212, USA.
Ana M Díaz-LasprillaEngineering Science Department, Trinity University, San Antonio, TX 78212, USA.
Gustavo E Ramírez-CaballeroEngineering Science Department, Trinity University, San Antonio, TX 78212, USA.
Dany J Munoz-PintoEngineering Science Department, Trinity University, San Antonio, TX 78212, USA.
Trinity University · US

Funding

John L. Santikos Charitable Foundation of the San Antonio Area Foundation NA
6 · The paper itself

Abstract

Growth factors (GF) are critical cytokines in wound healing. However, the direct delivery of these biochemical cues into a wound site significantly increases the cost of wound dressings and can lead to a strong immunological response due to the introduction of a foreign source of GFs. To overcome this challenge, we designed a poly(ethylene glycol) diacrylate (PEGDA) hydrogel with the potential capacity to sequester autologous GFs directly from the wound site. We demonstrated that synthetic peptide sequences covalently tethered to PEGDA hydrogels physically retained human transforming growth factor beta 1 (hTGFβ1) and human vascular endothelial growth factor (hVEGF) at 3.2 and 0.6 ng/mm

Indexed as

binding peptidesgrowth factorshuman dermal fibroblastshydrogels

Identifiers

PMID36661794
PMCPMC9857753
OpenAlexW4313409750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.