Evidence map›Paper›PMID 36661741›Full record

ArticleCurrent oncology (Toronto, Ont.)2023

Purely Off-Clamp Laparoscopic Partial Nephrectomy Stands the Test of Time: 15 Years Functional and Oncologic Outcomes from a Single Center Experience.

Aldo Brassetti, Umberto Anceschi, Alfredo Maria Bove, Francesco Prata, Manuela Costantini, Mariaconsiglia Ferriero, Riccardo Mastroianni, Leonardo Misuraca, Gabriele Tuderti, Giulia Torregiani and 3 more

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Aldo BrassettiDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.ORCID 0000-0001-9643-8979
Umberto AnceschiDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.ORCID 0000-0002-7586-4132
Alfredo Maria BoveDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.
Francesco PrataDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.ORCID 0000-0003-3084-6210
Manuela CostantiniDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.
Mariaconsiglia FerrieroDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.
Riccardo MastroianniDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.
Leonardo MisuracaDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.
Gabriele TudertiDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.ORCID 0000-0003-4480-9090
Giulia TorregianiDepartment of Anesthesiology, IRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.
Marco CovottaDepartment of Anesthesiology, IRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.
Michele GallucciDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.
Giuseppe SimoneDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.ORCID 0000-0002-4868-9025
Istituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNephron-sparing surgery represents the gold standard treatment for organ-confined renal tumors. We present 15-years of outcomes after off-clamp laparoscopic partial nephrectomy (ocLPN).

methodsa retrospective analysis was performed on patients who underwent ocLPN between May 2001 and December 2005. Baseline demographic, clinical, pathologic, surgical, functional and survival data were collected. The Kaplan-Meier method evaluated group-specific oncologic outcomes at 5, 10 and 15 years and the log rank test assessed differences between groups. The same analysis investigated the probabilities of developing a significant renal function impairment (sRFI) and achieving

resultsWe included 63 patients whose median tumor size was 3 cm (IQR:2-4). At 15 years, the chances of developing local recurrence, metachronous renal cancers or distant metastases were 2 ± 2%, 23 ± 6% and 17 ± 5%, respectively. Consequently, disease-free, cancer-specific and overall-survival probabilities were 68 ± 6%, 90 ± 4% and 72 ± 6%. MCRSS and UCISS well predicted oncologic outcomes. Overall, nine (14%) patients experienced an sRFI and 33 (52%) achieved

conclusionsAt 15 years from ocLPN, most of patients will experience both excellent functional and oncologic outcomes.

Indexed as

Kidney NeoplasmsLaparoscopyHumansNephrectomyRetrospective StudiesTreatment Outcomelaparoscopylong term outcomespartial nephrectomyrenal cancersurvival

Identifiers

PMID36661741
PMCPMC9858317
OpenAlexW4316469573

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.