Evidence map›Paper›PMID 36661666›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Predicting Nomogram for Severe Oral Mucositis in Patients with Nasopharyngeal Carcinoma during Intensity-Modulated Radiation Therapy: A Retrospective Cohort Study.

Zhibing Liu, Lulu Huang, Housheng Wang, Zhiling Shi, Yaqin Huang, Lixing Liang, Rensheng Wang, Kai Hu

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Effect of modified Baduanjin exercise on nutritional status in patients with nasopharyngeal carcinoma: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  4. Review
  5. Evaluation of mid-treatmentQuantitative imaging in medicine and surgery · 2026
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  12. Machine learning prediction model for oral mucositis risk in head and neck radiotherapy: a preliminary study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zhibing LiuDepartment of Radiation Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Lulu HuangDepartment of Radiation Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Housheng WangDepartment of Radiation Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Zhiling ShiDepartment of Radiation Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Yaqin HuangDepartment of Radiation Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Lixing LiangDepartment of Radiation Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Rensheng WangDepartment of Radiation Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Kai HuDepartment of Radiation Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Guangxi Medical University · CNFirst Affiliated Hospital of GuangXi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOral mucositis is an acute adverse reaction with high incidence during radiotherapy. Severe oral mucositis can seriously affect patients' quality of life and compliance with radiotherapy. The aim of this study was to identify the risk factors for severe oral mucositis and to develop a nomogram for predicting severe oral mucositis in patients with nasopharyngeal carcinoma.

methodsOne hundred and ninety patients with nasopharyngeal carcinoma were retrospectively screened in this study. Least absolute shrinkage and selection operator regression and multivariate logistic regression analyses were performed to identify the best predictors of severe oral mucositis. A nomogram was constructed based on the factors. Finally, the discriminative ability of the nomogram was evaluated.

resultsFour independent factors predicting severe oral mucositis were identified: age, N stage, the cycle of induction chemotherapy, and dose-volumetric parameter V40 (%) of oral cavity. The area under the receiver of operating characteristic curve of the nomogram was 0.759 (95% confidence interval: 0.691-0.827).

conclusionsA predictive nomogram for severe oral mucositis was established and validated in this study. The nomogram provides a reliable and practical model for clinically predicting the probability of severe oral mucositis in patients with nasopharyngeal carcinoma before intensity-modulated radiation therapy.

Indexed as

Nasopharyngeal NeoplasmsStomatitisHumansNasopharyngeal CarcinomaNomogramsQuality of LifeRetrospective Studiesintensity-modulatednasopharyngeal carcinomanomogramsradiotherapystomatitis

Identifiers

PMID36661666
PMCPMC9857735
OpenAlexW4312100798

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.