Evidence map›Paper›PMID 36661562›Full record

ReviewDentistry journal2023

Minimally Invasive Non-Surgical Technique in the Treatment of Intrabony Defects-A Narrative Review.

Styliani Anoixiadou, Andreas Parashis, Ioannis Vouros

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Dentistry journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06625528 early_phase1active not recruitingnot on this map

The Efficacy of Lyophilized Platelet-Rich Fibrin in Treatment of Periodontal Intra-Bony Defects (A Comparative Clinical, Radiographic and Biochemical Study)

TypeinterventionalSponsorAl-Azhar UniversityRan2023 to 2025Enrolled36ConditionsTreatment of Periodontal Intra-bony DefectsArmsopen flap debridement
NCT07339605 narecruitingnot on this mapstarted 2024, after this paper: background citation

Clinical and Radiographic Outcomes After Flapless Approach of Intrabony Defects With the Application of Enamel Matrix Derivative Versus Hyaluronic Acid: A Randomized Controlled Clinical Trial

TypeinterventionalSponsorUniversity of ValenciaRan2024 to 2027Enrolled60ConditionsGuided Tissue Regeneration, Periodontal / Methods, Dental Enamel Proteins* / Therapeutic Use, Alveolar Bone Loss* / Therapy, Hyaluronic Acid* / Therapeutic UseArmsFlapless instrumentation of the defect following MINST in conjuction with NaOCl and hyaluronic acid application, Flapless instrumentation of the defect following MINST, root conditioning with EDTA and EMD application, Flapless instrumentation of the defect and product application simulation
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Styliani AnoixiadouDepartment of Periodontology, School of Dental Medicine, Aristotle University, 54124 Thessaloniki, Greece.ORCID 0000-0002-1914-2944
Andreas ParashisDepartment of Periodontology, School of Dental Medicine, Aristotle University, 54124 Thessaloniki, Greece.ORCID 0000-0003-3346-2204
Ioannis VourosDepartment of Periodontology, School of Dental Medicine, Aristotle University, 54124 Thessaloniki, Greece.ORCID 0000-0001-9863-4949

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrabony defects occur frequently in periodontitis and represent sites that, if left untreated, are at increased risk for disease progression. Although resective or repair procedures have been used to treat intrabony defects, aiming at their elimination, the treatment of choice is surgical periodontal regeneration. The development of periodontal regeneration in the last 30 years has followed two distinctive, though totally different, paths. The interest of researchers has so far focused on regenerative materials and products on one side, and on novel surgical approaches on the other side. In the area of materials and products, three different regenerative concepts have been explored namely, barrier membranes, bone grafts, and wound healing modifiers/biologics, plus many combinations of the aforementioned. In the area of surgical approaches, clinical innovation in flap design and handling, as well as minimally invasive approaches, has radically changed regenerative surgery. Recently, a minimally invasive non-surgical technique (MINST) for the treatment of intrabony defects was proposed. Initial clinical trials indicated comparable results to the surgical minimally invasive techniques in both clinical and radiographic outcomes. These results support the efficacy of this treatment approach. The aim of this review is to present the evidence on the application of minimally invasive non-surgical techniques and their efficacy in the treatment of intrabony defects.

Indexed as

intrabony defectsminimally invasive non-surgical techniqueperiodontal treatment

Identifiers

PMID36661562
PMCPMC9858434

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.