Evidence map›Paper›PMID 36661498›Full record

ReviewCurrent issues in molecular biology2022

LSD1 for the Targeted Regulation of Adipose Tissue.

Li Chen, Xuan Sun, Daidi Chen, Qingjun Gui

Open access · goldAbstract readReview
In one paragraph

Review in Current issues in molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. [ORY-1001 inhibits glioblastoma cell growth by downregulating the Notch/HES1 pathwayNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Li ChenResearch Lab for Clinical & Translational Medicine, Hengyang Medical School, University of South China, Hengyang 421009, China.
Xuan SunResearch Lab for Clinical & Translational Medicine, Hengyang Medical School, University of South China, Hengyang 421009, China.
Daidi ChenResearch Lab for Clinical & Translational Medicine, Hengyang Medical School, University of South China, Hengyang 421009, China.
Qingjun GuiResearch Lab for Clinical & Translational Medicine, Hengyang Medical School, University of South China, Hengyang 421009, China.
University of South China · CN

Funding

Innovative Training Program for College Students of Hunan Province S202210555065Innovative Training Program for College Students of Hunan Provincet S202212650002National Innovation training Project of Hunan Natural Science Foundation 2021jj30591scientific Research Project of Hunan Provincial Education Department 20A441
6 · The paper itself

Abstract

White and thermal (brown and beige) adipose tissue energy storage and oxidative regulation pathways play a central role in maintaining the energy balance throughout the body, and the dysregulation of these pathways is closely related to glucose and lipid metabolism disorders and adipose tissue dysfunction, including obesity, chronic inflammation, insulin resistance, mitochondrial dysfunction, and fibrosis. Recent epigenetic studies have identified the novel regulatory element LSD1, which controls the above parameters, and have provided new mechanistic possibilities for re-encoding the fate and function of adipocytes. In this review, we outline the current advances in adipocyte metabolism in physiology and disease and discuss possible strategies for LSD1 to alter the phenotype of adipose tissue and thus influence energy utilization to improve metabolic health.

Indexed as

adipose tissueepigeneticsLSD1metabolismobesity

Identifiers

PMID36661498
PMCPMC9857158
OpenAlexW4313415193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.