Evidence map›Paper›PMID 36661329›Full record

ArticleBlood advances2023

Acquired BTK mutations associated with resistance to noncovalent BTK inhibitors.

Jialei Qi, Sascha Endres, Deyan Yordanov Yosifov, Eugen Tausch, Rashmi Priyadharshini Dheenadayalan, Xiang Gao, Annika Müller, Christof Schneider, Daniel Mertens, Peter Gierschik and 3 more

Open access · goldAbstract readLetterComment
In one paragraph

Article in Blood advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
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  8. Review
  9. Bruton's Tyrosine Kinase (BTK) Mutations in Chronic Lymphocytic Leukemia (CLL): A Clinical View.Mediterranean journal of hematology and infectious diseases · 2025
    Review
  10. Review
  11. BTK inhibitors: past, present, and future.Trends in pharmacological sciences · 2024
    Review
  12. Article
  13. New Means and Challenges in the Targeting of BTK.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Review
  14. Review
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  16. Review
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jialei QiDivision of CLL, Department of Internal Medicine III, Ulm University, Ulm, Germany.ORCID 0000-0002-9168-2291
Sascha EndresInstitute of Experimental and Clinical Pharmacology, Toxicology and Pharmacology of Natural Products, Ulm University, Ulm, Germany.ORCID 0000-0002-7243-6829
Deyan Yordanov YosifovDivision of CLL, Department of Internal Medicine III, Ulm University, Ulm, Germany.ORCID 0000-0002-5473-4398
Eugen TauschDivision of CLL, Department of Internal Medicine III, Ulm University, Ulm, Germany.
Rashmi Priyadharshini DheenadayalanDivision of CLL, Department of Internal Medicine III, Ulm University, Ulm, Germany.
Xiang GaoDepartment of Internal Medicine III, Ulm University, Ulm, Germany.
Annika MüllerDivision of CLL, Department of Internal Medicine III, Ulm University, Ulm, Germany.
Christof SchneiderDivision of CLL, Department of Internal Medicine III, Ulm University, Ulm, Germany.
Daniel MertensDivision of CLL, Department of Internal Medicine III, Ulm University, Ulm, Germany.ORCID 0000-0003-0227-7188
Peter GierschikInstitute of Experimental and Clinical Pharmacology, Toxicology and Pharmacology of Natural Products, Ulm University, Ulm, Germany.ORCID 0000-0001-9295-5231
Martin WistInstitute of Experimental and Clinical Pharmacology, Toxicology and Pharmacology of Natural Products, Ulm University, Ulm, Germany.
Billy Michael Chelliah JebarajDivision of CLL, Department of Internal Medicine III, Ulm University, Ulm, Germany.ORCID 0000-0002-6188-1652
Stephan StilgenbauerDivision of CLL, Department of Internal Medicine III, Ulm University, Ulm, Germany.
Universität Ulm · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MutationAgammaglobulinaemia Tyrosine KinaseHumansAgammaglobulinaemia Tyrosine Kinase

Identifiers

PMID36661329
PMCPMC10539862
OpenAlexW4317538429

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.