Evidence map›Paper›PMID 36661065›Full record

ReviewPharmacogenomics2023

The frequency of rs2231142 in

Ola AlAzzeh, Youssef M Roman

Open access · greenAbstract readReview
In one paragraph

Review in Pharmacogenomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Major Allele Frequencies inJournal of personalized medicine · 2025
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. The frequency of majorPharmacogenomics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ola AlAzzehDepartment of Pharmacotherapy & Outcome Science, Virginia Commonwealth University School of Pharmacy, 410 N 12th Street, Richmond, VA 23298, USA.
Youssef M RomanDepartment of Pharmacotherapy & Outcome Science, Virginia Commonwealth University School of Pharmacy, 410 N 12th Street, Richmond, VA 23298, USA.ORCID 0000-0002-0613-5534
Virginia Commonwealth University · US

Funding

UH Hilo COP A&RP20GM103466 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI Peter R Hoffmann · 2012 to 2026
$60.3M
RESEARCH DESIGN AND BIOSTATISTICS COREU54MD007584 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI HEDGES, JERRIS ROBERT, MOKUAU, NOREEN · 2012 to 2018
$21.1M
RESEARCH DESIGN, BIOSTATISTICS AND RESEARCH ETHICS COREG12MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI BERRY, MARLA J · 2012 to 2016
$13.0M
NIGMS NIH HHS P20 GM103466NIMHD NIH HHS G12 MD007601NIMHD NIH HHS U54 MD007584
6 · The paper itself

Abstract

Statins are among the most commonly prescribed medications worldwide. Rosuvastatin is a moderate- to high-intensity statin depending on the prescribed dose. Statin-associated muscle symptoms are the main side effects, contributing to low adherence to statins. The missense variant rs2231142 in

Indexed as

ATP Binding Cassette Transporter, Subfamily G, Member 2Hydroxymethylglutaryl-CoA Reductase InhibitorsRosuvastatin CalciumHumansNative Hawaiian or Pacific IslanderNeoplasm ProteinsPolymorphism, Single NucleotideABCG2 protein, humanATP Binding Cassette Transporter, Subfamily G, Member 2Hydroxymethylglutaryl-CoA Reductase InhibitorsNeoplasm ProteinsRosuvastatin CalciumABCG2adverse drug eventsdrug transporter genesdyslipidemiaNative HawaiianPacific Islanderspharmacogeneticsracial minoritiesrosuvastatinstatins

Identifiers

PMID36661065
PMCPMC10072122
OpenAlexW4317532931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.