ArticleNucleic acids research2023
Cold-induced inhibition of photosynthesis-related genes integrated by a TOP6 complex in rice mesophyll cells.
Article in Nucleic acids research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Meta-analysis and dose-response analysis of low-temperature stress effects on rice yield and physiological responses.Frontiers in plant science · 2026Pooled it
- Multi-environment genome-wide association study reveals genetic loci associated with drought tolerance during wheat germination.Plant cell reports · 2026Article
- SlBBX19 modulates plant development and negatively regulates chilling tolerance in tomato.The Plant journal : for cell and molecular biology · 2026Article
- Multispectral Fluorescence Imaging for Fast Identification of Cold Stress in Pepper Plants.Sensors (Basel, Switzerland) · 2026Article
- Quick creation and mapping of EMS-induced maize kernel mutants identifies classical gene ZmBT1 and novel gene ZmTOP6A.The plant genome · 2026Article
- Article
- Integrated physiological, biochemical, and transcriptomic analysis of the cold-sensitive response in Mussaenda anomala.BMC genomics · 2025Article
- The phytochrome-interacting factor PIL13 enhances water use efficiency under fluctuating light and drought resilience in rice and soybean.Communications biology · 2025Article
- Brassinosteroid-mediated carotenoid regulation enhances chilling tolerance in pepper.BMC genomics · 2025Article
- Integrative analysis of transcriptome and metabolism reveals functional roles of redox homeostasis in low light and salt combined stress in Leymus chinensis.BMC genomics · 2025Article
- Time-course transcriptome analysis reveals gene co-expression networks and transposable element responses to cold stress in cotton.BMC genomics · 2025Article
- Identifications of Genes Involved in ABA and MAPK Signaling Pathways Positively Regulating Cold Tolerance in Rice.Plants (Basel, Switzerland) · 2025Article
- Combined analysis of proteomics and metabolism reveals critical roles of oxidoreductase activity in mushrooms stimulated by wolfberry and sea buckthorn substrates.Frontiers in nutrition · 2025Article
- Integrating Proteomics and Metabolomics Approaches to Elucidate the Mechanism of Responses to Combined Stress in the Bell Pepper (Plants (Basel, Switzerland) · 2024Article
- The Molecular Mechanism of Cold-Stress Tolerance: Cold Responsive Genes and Their Mechanisms in Rice (Biology · 2024Review
- The MRE11-ATM-SOG1 DNA damage signaling pathway confers rice immunity to Xanthomonas oryzae.Plant communications · 2024Article
- Effects of exogenous glycine betaine on growth and development of tomato seedlings under cold stress.Frontiers in plant science · 2024Article
- Transcriptome analyses reveal photosynthesis-related genes involved in photosynthetic regulation under low temperature stress inFrontiers in plant science · 2023Article
- Effect of gibberellic acid on photosynthesis and oxidative stress response in maize under weak light conditions.Frontiers in plant science · 2023Article
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Authors and funding
8 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Photosynthesis is the most temperature-sensitive process in the plant kingdom, but how the photosynthetic pathway responds during low-temperature exposure remains unclear. Herein, cold stress (4°C) induced widespread damage in the form DNA double-stranded breaks (DSBs) in the mesophyll cells of rice (Oryza sativa), subsequently causing a global inhibition of photosynthetic carbon metabolism (PCM) gene expression. Topoisomerase genes TOP6A3 and TOP6B were induced at 4°C and their encoded proteins formed a complex in the nucleus. TOP6A3 directly interacted with KU70 to inhibit its binding to cold-induced DSBs, which was facilitated by TOP6B, finally blocking the loading of LIG4, a component of the classic non-homologous end joining (c-NHEJ) pathway. The repression of c-NHEJ repair imposed by cold extended DSB damage signaling, thus prolonging the inhibition of photosynthesis in leaves. Furthermore, the TOP6 complex negatively regulated 13 crucial PCM genes by directly binding to their proximal promoter regions. Phenotypically, TOP6A3 overexpression exacerbated the γ-irradiation-triggered suppression of PCM genes and led to the hypersensitivity of photosynthesis parameters to cold stress, dependent on the DSB signal transducer ATM. Globally, the TOP6 complex acts as a signal integrator to control PCM gene expression and synchronize cold-induced photosynthesis inhibition, which modulates carbon assimilation rates immediately in response to changes in ambient temperature.
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