ArticleEuropean heart journal2023
Lifestyle habits associated with cardiac conduction disease.
Article in European heart journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Comparative outcomes of Myval versus contemporary transcatheter heart valves: a systematic review and meta-analysis.Cardiovascular intervention and therapeutics · 2025Pooled it
- Incidence and prognosis of cardiac conduction system diseases in hypertension: the STEP trial.Nature aging · 2024Trial
- Weighted hybrid score predicts outflow tract ventricular arrhythmia origin in patients with intraventricular conduction disorders or paced rhythm: an international multicenter study.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Lean body mass is the independent and predominant anthropometric variable associated with atrioventricular block.Heart rhythm O2 · 2026Article
- Associations Between Accelerometer-Measured 24-Hour Movement Behaviors and Cardiac Conduction Disease in the UK Biobank Cohort.Korean circulation journal · 2026Article
- Left Ventricular Ejection Fraction and Incident Cardiac Conduction Dysfunction: Exploring the Mediating Effects of Electrophysiological Parameters.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026Article
- A Clinical Exploration of One of the Longest Documented Ventricular Pauses in an Ambulatory Patient.Case reports in cardiology · 2026Article
- Modifiable predictors of atrioventricular block warranting a pacemaker: A cohort study.PloS one · 2026Article
- Association of Epicardial Adipose Tissue With Bradyarrhythmias: A Matched Case-Control Study.Journal of the American Heart Association · 2025Article
- Artificial Intelligence-Enhanced Electrocardiography for Complete Heart Block Risk Stratification.JAMA cardiology · 2025Article
- Trends in cardiac conduction disorder-associated mortality among young adults in the United States, 2010-2020.Heart rhythm O2 · 2025Article
- Association Between Modifiable Lifestyle Factors and Incident Cardiac Conduction Disease.JACC. Asia · 2025Article
- Association Between Cumulative Body Mass Index Exposure and the Risk of Incident Cardiac Conduction Block.Journal of the American Heart Association · 2025Article
- Blood Pressure Control and Incident Left-Ventricular Conduction Disease.Current cardiology reports · 2025Review
- Time-Weighted Cumulative High-Sensitivity C-Reactive Protein and Risk of Cardiac Conduction Block: Findings from a Prospective Cohort.Journal of inflammation research · 2025Article
- Association between obesity and cardiac conduction defects.Frontiers in cardiovascular medicine · 2025Article
- The integral role of lifestyle in the prevention and management of hypertension and associated cardiometabolic and cognitive disorders: a review.Frontiers in endocrinology · 2025Review
- [Intrinsic steady-state pattern of mouse cardiac electrophysiology: analysis using a characterized quantitative electrocardiogram strategy].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Article
- Physical Activity Modifies the Risk of Incident Cardiac Conduction Disorders Upon Inflammation: A Population-Based Cohort Study.Journal of the American Heart Association · 2024Article
- Obesity and physical inactivity are associated with increased risks of cardiac conduction disease: a report from the Kailuan Cohort Study.NPJ cardiovascular health · 2024Article
Corrections and comments
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8 authors at 5 institutions in 2 countries.
Funding
Abstract
aimsCardiac conduction disease can lead to syncope, heart failure, and death. The only available therapy is pacemaker implantation, with no established prevention strategies. Research to identify modifiable risk factors has been scant. METHODS AND
resultsData from the Cardiovascular Health Study, a population-based cohort study of adults ≥ 65 years with annual 12-lead electrocardiograms obtained over 10 years, were utilized to examine relationships between baseline characteristics, including lifestyle habits, and conduction disease. Of 5050 participants (mean age 73 ± 6 years; 52% women), prevalent conduction disease included 257 with first-degree atrioventricular block, 99 with left anterior fascicular block, 9 with left posterior fascicular block, 193 with right bundle branch block (BBB), 76 with left BBB, and 102 with intraventricular block at baseline. After multivariable adjustment, older age, male sex, a larger body mass index, hypertension, and coronary heart disease were associated with a higher prevalence of conduction disease, whereas White race and more physical activity were associated with a lower prevalence. Over a median follow-up on 7 (interquartile range 1-9) years, 1036 developed incident conduction disease. Older age, male sex, a larger BMI, and diabetes were each associated with incident conduction disease. Of lifestyle habits, more physical activity (hazard ratio 0.91, 95% confidence interval 0.84-0.98, P = 0.017) was associated with a reduced risk, while smoking and alcohol did not exhibit a significant association.
conclusionWhile some difficult to control comorbidities were associated with conduction disease as expected, a readily modifiable lifestyle factor, physical activity, was associated with a lower risk.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.