Evidence map›Paper›PMID 36660724›Full record

ArticleAnnals of translational medicine2022

Dosimetric impacts of cone-beam computed tomography (CBCT)-based anatomic changes in intensity-modulated radiotherapy for cervical cancer.

Han Yang, Xiujuan Zhao, Yang He, Xia Tan, Haiyan Peng, Mingsong Zhong, Qicheng Li, Xianfeng Liu, Yanan He, Huanli Luo and 1 more

Abstract read
In one paragraph

Article in Annals of translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Han YangDepartment of Radiation Oncology, Chongqing University Cancer Hospital, Chongqing, China.
Xiujuan ZhaoDepartment of Gynecological Oncology, Chongqing University Cancer Hospital, Chongqing, China.
Yang HeDepartment of Radiation Oncology, Chongqing University Cancer Hospital, Chongqing, China.
Xia TanDepartment of Radiation Oncology, Chongqing University Cancer Hospital, Chongqing, China.
Haiyan PengDepartment of Radiation Oncology, Chongqing University Cancer Hospital, Chongqing, China.
Mingsong ZhongDepartment of Radiation Oncology, Chongqing University Cancer Hospital, Chongqing, China.
Qicheng LiDepartment of Radiation Oncology, Chongqing University Cancer Hospital, Chongqing, China.
Xianfeng LiuDepartment of Radiation Oncology, Chongqing University Cancer Hospital, Chongqing, China.
Yanan HeDepartment of Radiation Oncology, Chongqing University Cancer Hospital, Chongqing, China.
Huanli LuoDepartment of Radiation Oncology, Chongqing University Cancer Hospital, Chongqing, China.
Fu JinDepartment of Radiation Oncology, Chongqing University Cancer Hospital, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To evaluate the effects of dose to tumors and organs at risk (OARs) on inter-fractional anatomic changes. Methods: We evaluated nine patients with cervical cancer treated with intensity-modulated radiotherapy (IMRT) (45 Gy in 25 fractions) using kV cone-beam computed tomography (CBCT) image guidance once or twice a week before treatment. For each patient, the original plan on the computed tomography (CT) image was copied to merged images, and then the fractional doses were calculated. Subsequently, deformable accumulated doses were obtained by summing the fractional absolute doses into a single dose in MIM Maestro software. The volume changes in the target and OARs were compared between the original CT and merged CBCT images, and the differences in the fractional and accumulated doses were also evaluated. Results: Sixty-nine merged CBCT images were obtained and analyzed in this study. For the target areas, the volume changes in the clinical target volume (CTV) and planning target volume (PTV) reached -18.05% and -24.11% at most, respectively. The fractional D Conclusions: For patients with cervical cancer, the changes in bladder and rectal volume were greater than in the target volume. Although the volume changes in the bladder and rectum had no significant effect on D

Indexed as

anatomic changesCBCT-based dose calculationdeformation dosedosimetric uncertaintiesMerged cone-beam computed tomography image (merged CBCT image)

Identifiers

PMID36660724
PMCPMC9843308

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.