Evidence map›Paper›PMID 36660171›Full record

ReviewGlobal cardiology science & practice2022

Middle aortic syndrome in children and adolescents.

Mustafa Musajee, Marisa Gasparini, Douglas J Stewart, Narayan Karunanithy, Manish D Sinha, Morad Sallam

Open access · diamondAbstract readReview
In one paragraph

Review in Global cardiology science & practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Mid-aortic syndrome in two Saudi children with refractory hypertension: a case report.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Pediatric Renovascular Hypertension: Diagnosis and Management.Seminars in interventional radiology · 2025
    Review
  7. Article
  8. Article
  9. Middle aortic syndrome in childhood-onset Takayasu arteritis.Journal of vascular surgery cases and innovative techniques · 2025
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mustafa MusajeeDepartment of Vascular Surgery, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Marisa GaspariniDepartment of Vascular Surgery, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Douglas J StewartDepartment of Paediatric Nephrology, Evelina London Children's Hospital, Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom.
Narayan KarunanithySchool of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
Manish D SinhaDepartment of Paediatric Nephrology, Evelina London Children's Hospital, Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom.
Morad SallamDepartment of Vascular Surgery, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Guy's and St Thomas' NHS Foundation Trust · GBKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Middle aortic syndrome is a rare form of renovascular disease that may present with severe hypertension during childhood. Narrowing of the abdominal aorta is often associated with narrowing of the renal and/or other visceral arteries and may be secondary to specific genetic syndromes. Following the optimization of blood pressure control, significant aortic narrowing often requires invasive management, including endovascular and surgical intervention. In younger children, endovascular therapy may be attempted in the first instance to acutely reduce the pressure gradient across the narrowing; however, a sustained benefit is rare. Once the child has grown to accommodate a graft of an adequate size, surgical therapy is indicated for patients in whom medical and/or endovascular management has not resulted in adequate blood pressure control. It is critical that individuals with middle aortic syndrome be managed by an experienced multidisciplinary team that includes medical, endovascular, and surgical expertise that can provide long-term care to monitor for recurrent hypertension and evidence of end-organ damage.

Identifiers

PMID36660171
PMCPMC9840135
OpenAlexW4311008621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.