Evidence map›Paper›PMID 36660076›Full record

ReviewAIMS neuroscience2022

Chronic traumatic encephalopathy: Diagnostic updates and advances.

Kevin Pierre, Vanessa Molina, Shil Shukla, Anthony Avila, Nicholas Fong, Jessica Nguyen, Brandon Lucke-Wold

Open access · goldAbstract readReview
In one paragraph

Review in AIMS neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kevin PierreUniversity of Florida Department of Radiology, Gainesville 32603, Florida, USA.
Vanessa MolinaSam Houston State University of Osteopathic Medicine, Conroe 77304, Texas, USA.
Shil ShuklaSam Houston State University of Osteopathic Medicine, Conroe 77304, Texas, USA.
Anthony AvilaSam Houston State University of Osteopathic Medicine, Conroe 77304, Texas, USA.
Nicholas FongSam Houston State University of Osteopathic Medicine, Conroe 77304, Texas, USA.
Jessica NguyenSam Houston State University of Osteopathic Medicine, Conroe 77304, Texas, USA.
Brandon Lucke-WoldUniversity of Florida Department of Neurosurgery, Gainesville 32603, Florida, USA.
Sam Houston State University · USUniversity of Florida · US

Funding

University of Florida R25 Early Research Program for Neurology and Neurosurgery ResidentsR25NS108939 · NINDS · UNIVERSITY OF FLORIDA · PI HOH, BRIAN LIM, HOH, BRIAN LIM · 2019 to 2024
$537k
NINDS NIH HHS R25 NS108939
6 · The paper itself

Abstract

Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease that occurs secondary to repetitive mild traumatic brain injury. Current clinical diagnosis relies on symptomatology and structural imaging findings which often vary widely among those with the disease. The gold standard of diagnosis is post-mortem pathological examination. In this review article, we provide a brief introduction to CTE, current diagnostic workup and the promising research on imaging and fluid biomarker diagnostic techniques. For imaging, we discuss quantitative structural analyses, DTI, fMRI, MRS, SWI and PET CT. For fluid biomarkers, we discuss p-tau, TREM2, CCL11, NfL and GFAP.

Indexed as

chronic traumatic encephalopathydiagnosticsmanagementwork up

Identifiers

PMID36660076
PMCPMC9826753
OpenAlexW4313209744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.