ArticleJournal of multidisciplinary healthcare2023
Triglyceride Glucose Index Increases Significantly Risk of Hypertension Development in Chinese Individuals Aged ≥45 Years Old: Analysis from the China Health and Retirement Longitudinal Study.
Article in Journal of multidisciplinary healthcare, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- The triglyceride-glucose index is associated with a higher risk of hypertension: evidence from a cross-sectional study of Chinese adults and meta-analysis of epidemiology studies.Frontiers in endocrinology · 2025Pooled it
- Association between triglyceride-glucose index and hypertension: A systematic review and meta-analysis.Narra J · 2024Pooled it
- Discordance between remnant cholesterol and low-density lipoprotein cholesterol predicts incident hypertension: a 9-year prospective cohort study in Chinese adults.BMC cardiovascular disorders · 2026Article
- Triglyceride-glucose index and abnormal blood pressure in adults aged over 70 years: real-world data evidence.BMC cardiovascular disorders · 2026Article
- Cumulative exposure to remnant cholesterol and new-onset hypertension in middle-aged and older adults: a nationwide prospective cohort study with mediation analysis.Journal of human hypertension · 2026Article
- A Link Between the Triglyceride-Glucose Index and the Risk of Hypertension Among Employees in the Titanium Dioxide Industry.Vascular health and risk management · 2026Article
- Triglyceride-glucose index, HOmeostatic Model Assessment index, and new-onset hypertension in middle-aged men.Journal of hypertension · 2026Article
- TyG Index and Related Indices Predicting Hypertension: Mediation by Neutrophil-to-Lymphocyte Ratio in Multiple Chinese Cohorts.Nutrients · 2025Article
- Non-linear relationship between triglyceride glucose index and new-onset diabetes among individuals with non-alcoholic fatty liver disease: a cohort study.Lipids in health and disease · 2025Article
- Cardiometabolic index predicts cardiovascular events in aging population: a machine learning-based risk prediction framework from a large-scale longitudinal study.Frontiers in endocrinology · 2025Article
- Associations of triglyceride-glucose index and metabolic score for insulin resistance with various hypertension phenotypes in children and adolescents: results from the 2017 China nutrition and health surveillance.Frontiers in endocrinology · 2025Article
- Sex-specific associations between the triglyceride-glucose index and new-onset hypertension in a hospital employee cohort: evidence from longitudinal annual health examinations.Frontiers in endocrinology · 2025Article
- Relationship of the metabolic score for insulin resistance and the new-onset hypertension: Evidence from CHARLS.PloS one · 2025Article
- Article
- Gender differences in the association between changes in the atherogenic index of plasma and cardiometabolic diseases: a cohort study.Lipids in health and disease · 2024Article
- Prediction of various insulin resistance indices for the risk of hypertension among military young adults: the CHIEF cohort study, 2014-2020.Cardiovascular diabetology · 2024Article
- The effect of insulin resistance in the association between obesity and hypertension incidence among Chinese middle-aged and older adults: data from China health and retirement longitudinal study (CHARLS).Frontiers in public health · 2024Article
- Association of hypertension with the triglyceride-glucose index and its associated indices in the Chinese population: A 6-year prospective cohort study.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Combined effect of triglyceride glucose-body mass index and hypertension on new-onset stroke: evidence from the China health and retirement longitudinal study.Frontiers in public health · 2024Article
- Association of TyG index with hypertension in Chinese adults: the China Health Examination Collaborative Study (CHEC Study).Asia Pacific journal of clinical nutrition · 2023Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Our purpose was to explore the relationship between triglyceride glucose (TyG) index and the risk of new-onset hypertension in Chinese individuals aged ≥45 years. Methods: From 2011 to 2018, data from the China Health and Retirement Longitudinal Survey (CHARLS) were analyzed. The relationship between TyG index and hypertension was assessed utilizing Cox regression and restricted cubic spline (RCS) plot, and the importance of the TyG index in hypertension development was demonstrated by a random forest machine learning model. Finally, subgroup analysis was conducted to test for potential interactions on hypertension development between the TyG index and subgroups. Results: 19.7% of the 4755 individuals who were involved in this survey developed hypertension over an average follow-up period of 5.22 years. Compared with the first quartile of albumin, the multivariate HR (95% CI) for the risk of new-onset hypertension across the TyG index quartiles was 1.09 (0.89, 1.33), 1.09 (0.89, 1.33), and 1.29 (1.06, 1.58), respectively ( Conclusion: TyG index was an independent hazard indicator for new-onset hypertension, and routine measurement and control of TyG index level might be great for preventing hypertension development.
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