Evidence map›Paper›PMID 36660007›Full record

ReviewTranslational neuroscience2022

Brain and gut microbiota disorders in the psychopathology of anorexia nervosa.

Mercedes Garcia-Gil, Maria Rachele Ceccarini, Fabrizio Stoppini, Samuela Cataldi, Claudia Mazzeschi, Elisa Delvecchio, Elisabetta Albi, Giulia Gizzi

Open access · goldAbstract readReview
In one paragraph

Review in Translational neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mercedes Garcia-GilDepartment of Biology, University of Pisa, 56127, Pisa, Italy.
Maria Rachele CeccariniDepartment of Pharmaceutical Science, University of Perugia, 06126 Perugia, Italy.
Fabrizio StoppiniDepartment of Pharmaceutical Science, University of Perugia, 06126 Perugia, Italy.
Samuela CataldiDepartment of Pharmaceutical Science, University of Perugia, 06126 Perugia, Italy.
Claudia MazzeschiDepartment of Philosophy, Social Sciences and Education, University of Perugia, 06126 Perugia, Italy.
Elisa DelvecchioDepartment of Philosophy, Social Sciences and Education, University of Perugia, 06126 Perugia, Italy.
Elisabetta AlbiDepartment of Pharmaceutical Science, University of Perugia, 06126 Perugia, Italy.
Giulia GizziDepartment of Philosophy, Social Sciences and Education, University of Perugia, 06126 Perugia, Italy.
University of Perugia · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies of pathophysiological mechanisms involved in eating disorders (EDs) have intensified over the past several years, revealing their unprecedented and unanticipated complexity. Results from many articles highlight critical aspects in each member of ED family. Notably, anorexia nervosa (AN) is a disorder due to undefined etiology, frequently associated with symptoms of depression, anxiety, obsessive-compulsiveness, accompanied by endocrine alterations, altered immune response, increased inflammation, and dysbiosis of the gut microbiota. Hence, an advanced knowledge of how and why a multisystem involvement exists is of paramount importance to understand the pathogenetic mechanisms of AN. In this review, we describe the change in the brain structure/function focusing on hypothalamic endocrine disorders and the disequilibrium of gut microbiota in AN that might be responsible for the psychopathological complication.

Indexed as

anorexia nervosaeating disordersgut microbiotahypothalamic disorders

Identifiers

PMID36660007
PMCPMC9824428
OpenAlexW4313653859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.