Evidence map›Paper›PMID 36659967›Full record

ArticleNeuro-oncology practice2023

Molecular marker testing and reporting completeness for adult-type diffuse gliomas in the United States.

Corey Neff, Gino Cioffi, Kristin Waite, Carol Kruchko, Jill S Barnholtz-Sloan, Quinn T Ostrom, J Bryan Iorgulescu

Open access · hybridAbstract read
In one paragraph

Article in Neuro-oncology practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Corey NeffCentral Brain Tumor Registry of the United States, Hinsdale, IL, USA.ORCID https://orcid.org/0000-0001-9479-2747
Gino CioffiCentral Brain Tumor Registry of the United States, Hinsdale, IL, USA.ORCID https://orcid.org/0000-0002-3296-8652
Kristin WaiteCentral Brain Tumor Registry of the United States, Hinsdale, IL, USA.
Carol KruchkoCentral Brain Tumor Registry of the United States, Hinsdale, IL, USA.ORCID https://orcid.org/0000-0001-7212-035X
Jill S Barnholtz-SloanCentral Brain Tumor Registry of the United States, Hinsdale, IL, USA.
Quinn T OstromCentral Brain Tumor Registry of the United States, Hinsdale, IL, USA.
J Bryan IorgulescuCentral Brain Tumor Registry of the United States, Hinsdale, IL, USA.
Central Brain Tumor Registry of the United States · USDuke University · USBrigham and Women's Hospital · US

Funding

Training Program in Nervous System TumorsK12CA090354 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI PLOTKIN, SCOTT R · 2001 to 2025
$16.3M
NCI NIH HHS K12 CA090354
6 · The paper itself

Abstract

Background: A newly developed brain molecular marker (BMM) data item was implemented by US cancer registries for individuals diagnosed with brain tumors in 2018-including IDH and 1p/19q-co-deletion statuses for adult-type diffuse gliomas. We thus investigated the testing/reporting completeness of BMM in the United States. Methods: Cases of histopathologically confirmed glioblastoma, astrocytoma, and oligodendroglioma diagnosed in 2018 were identified in the National Cancer Database. Adjusted odds ratios (OR Results: Among 8306 histopathologically diagnosed adult-type diffuse gliomas nationally, overall BMM testing/reporting completeness was 81.1%. Compared to biopsy-only cases, odds of testing/reporting increased for subtotal (OR Conclusions: Initial BMM testing/reporting completeness for individuals with adult-type diffuse gliomas in the United States was promising, although patterns varied by hospital attributes and extent of resection.

Indexed as

brain molecular markersdiffuse gliomaglioblastomaIDH mutationMGMT promoter methylation

Identifiers

PMID36659967
PMCPMC9837780
OpenAlexW4303418743

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.