ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023
Synthesis and Functionalization of Graphene Materials for Biomedical Applications: Recent Advances, Challenges, and Perspectives.
Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 103 citations in OpenAlex.
- Closing the Loop: High-Precision 3D Photofabrication in Living Tissues.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- High-Performance Prevascularized SHED-Laden rGO@Hydrogel Achieves Optimized Diabetic Bone Defect Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Systemic Effects of Repeated Intraperitoneal Application of Graphene Oxide and Polyethylene Glycol-Functionalized Graphene Oxide Nanoparticles in Long Evans Male Rats.International journal of molecular sciences · 2026Article
- Free-Standing Boron-Doped Graphene Hydrogel Buckypaper Fabricated via Zinc-Plate Reduction for High-Performance Supercapacitors.ACS applied materials & interfaces · 2026Article
- Thermo-responsive shape memory biomaterials with structural and physical adaptivity for scarless personalized nerve repair.Materials today. Bio · 2025Article
- Harnessing light: Synthesis, mechanisms, and pre-clinical biomedical applications of stimuli-responsive multiscale composites.Materials today. Bio · 2025Review
- Biodegradable graphene nanocomposites as functional biomaterials: a review of their role in controlled drug delivery and tissue engineering.RSC advances · 2025Review
- Progress in the Application of Nanomaterials in Tumor Treatment.Biomedicines · 2025Review
- Turning Waste into Sensors: Sustainable Pesticide Detection Using Orange Peel-Derived Laser-Induced Graphene.ACS omega · 2025Article
- Self-adhesion conductive cardiac patch based on methoxytriethylene glycol-functionalized graphene effectively improves cardiac function after myocardial infarction.Journal of advanced research · 2025Article
- Material-Driven Therapeutics: Functional Nanomaterial Design Paradigms Revolutionizing Osteosarcoma Treatment.Journal of functional biomaterials · 2025Review
- Multifunctional Conductive Nanofibers for Self-Powered Glucose Biosensors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Prussian-Blue Catalysis and NFC Synergy: a Battery-Free Laser-Induced Graphene-Based Platform for Urine Glucose Monitoring at Point-of-Care.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Room-Temperature Ammonia Sensing Using Polyaniline-Coated Laser-Induced Graphene.Sensors (Basel, Switzerland) · 2024Article
- Thermal Stability and Purity of Graphene and Carbon Nanotubes: Key Parameters for Their Thermogravimetric Analysis (TGA).Nanomaterials (Basel, Switzerland) · 2024Article
- Modification Strategies for Development of 2D Material-Based Electrocatalysts for Alcohol Oxidation Reaction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Non-Cytotoxic Graphene Nanoplatelets Upregulate Cell Proliferation and Self-Renewal Genes of Mesenchymal Stem Cells.International journal of molecular sciences · 2024Article
- Graphene and its hybrid nanocomposite: A Metamorphoses elevation in the field of tissue engineering.Heliyon · 2024Review
- Recent advances in graphene-based electroanalytical devices for healthcare applications.Nanoscale · 2024Review
- AI energized hydrogel design, optimization and application in biomedicine.Materials today. Bio · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
Since its discovery in 2004, graphene is increasingly applied in various fields owing to its unique properties. Graphene application in the biomedical domain is promising and intriguing as an emerging 2D material with a high surface area, good mechanical properties, and unrivalled electronic and physical properties. This review summarizes six typical synthesis methods to fabricate pristine graphene (p-G), graphene oxide (GO), and reduced graphene oxide (rGO), followed by characterization techniques to examine the obtained graphene materials. As bare graphene is generally undesirable in vivo and in vitro, functionalization methods to reduce toxicity, increase biocompatibility, and provide more functionalities are demonstrated. Subsequently, in vivo and in vitro behaviors of various bare and functionalized graphene materials are discussed to evaluate the functionalization effects. Reasonable control of dose (<20 mg kg
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.