Evidence map›Paper›PMID 36658611›Full record

ArticleTrials2023

Telehealth multicomponent exercise and health education in breast cancer patients undergoing primary treatment: rationale and methodological protocol for a randomized clinical trial (ABRACE: Telehealth).

João S Henkin, Cíntia E Botton, Mariana S Simon, Guilherme G Rocha, Caroline B Silveira, Ricardo S Gehrke, Gabriella B Freitas, Gabriel S Trajano, Ronei S Pinto, Stephanie S Pinto

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04641377 (A Multicomponent Exercise Intervention Using Telehealth to Improve Psychological and Physical Outcomes in Breast Cancer Patients Undergoing Primary Treatment), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04641377 naunknown statusnot on this map

A Multicomponent Exercise Intervention Using Telehealth to Improve Psychological and Physical Outcomes in Breast Cancer Patients Undergoing Primary Treatment: A Randomized Controlled Trial

TypeinterventionalSponsorFederal University of PelotasRan2021 to 2023Enrolled36ConditionsBreast Cancer FemaleArmsMulticomponent exercise intervention plus health education, Health Education
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

João S HenkinExercise Research Laboratory (LAPEX), Physical Education, Physiotherapy, and Dance School, Universidade Federal do Rio Grande do Sul (UFRGS), Rua Felizardo, 750 - Bairro Jardim Botânico, Porto Alegre, Rio Grande do Sul, CEP: 90690-200, Brazil. joaohenkin@gmail.com.ORCID http://orcid.org/0000-0003-2909-1543
Cíntia E BottonExercise Pathophysiology Research Laboratory, Hospital de Clínicas de Porto Alegre, Clinical Research Center, Porto Alegre, Rio Grande do Sul, Brazil.
Mariana S SimonExercise Research Laboratory (LAPEX), Physical Education, Physiotherapy, and Dance School, Universidade Federal do Rio Grande do Sul (UFRGS), Rua Felizardo, 750 - Bairro Jardim Botânico, Porto Alegre, Rio Grande do Sul, CEP: 90690-200, Brazil.
Guilherme G RochaExercise Research Laboratory (LAPEX), Physical Education, Physiotherapy, and Dance School, Universidade Federal do Rio Grande do Sul (UFRGS), Rua Felizardo, 750 - Bairro Jardim Botânico, Porto Alegre, Rio Grande do Sul, CEP: 90690-200, Brazil.
Caroline B SilveiraExercise Research Laboratory (LAPEX), Physical Education, Physiotherapy, and Dance School, Universidade Federal do Rio Grande do Sul (UFRGS), Rua Felizardo, 750 - Bairro Jardim Botânico, Porto Alegre, Rio Grande do Sul, CEP: 90690-200, Brazil.
Ricardo S GehrkeExercise Research Laboratory (LAPEX), Physical Education, Physiotherapy, and Dance School, Universidade Federal do Rio Grande do Sul (UFRGS), Rua Felizardo, 750 - Bairro Jardim Botânico, Porto Alegre, Rio Grande do Sul, CEP: 90690-200, Brazil.
Gabriella B FreitasExercise Research Laboratory (LAPEX), Physical Education, Physiotherapy, and Dance School, Universidade Federal do Rio Grande do Sul (UFRGS), Rua Felizardo, 750 - Bairro Jardim Botânico, Porto Alegre, Rio Grande do Sul, CEP: 90690-200, Brazil.
Gabriel S TrajanoSchool of Exercise and Nutrition Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Australia.
Ronei S Pinto *Exercise Research Laboratory (LAPEX), Physical Education, Physiotherapy, and Dance School, Universidade Federal do Rio Grande do Sul (UFRGS), Rua Felizardo, 750 - Bairro Jardim Botânico, Porto Alegre, Rio Grande do Sul, CEP: 90690-200, Brazil.
Stephanie S Pinto *Neuromuscular Assessment Laboratory, Physical Education School, Universidade Federal de Pelotas, Pelotas, Rio Grande do Sul, Brazil.
Universidade Federal do Rio Grande do Sul · BRHospital de Clínicas de Porto Alegre · BRQueensland University of Technology · AUUniversidade Federal de Pelotas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrent guidelines emphasize cancer patients should increase their physical activity levels, encouraging physical exercise practice as a complementary therapy to mitigate adverse effects during treatment. Telehealth can be a feasible method to improve adherence and interventional support for breast cancer patients, of which most do not meet sufficient physical activity levels after diagnosis. The Adaptations to Breast Cancer and Exercise Using Telehealth (ABRACE: Telehealth) study aims to investigate the effects of a 12-week telehealth multicomponent training program plus a health education program (MTHE), compared to a health education program alone (HE), on physical and psychological outcomes in breast cancer patients undergoing treatment.

methodsThis study is a randomized controlled trial. Women undergoing primary treatment (during or after chemotherapy) for breast cancer (stages I-III) will be randomly assigned to MTHE (twice a week) or HE (once a week). MTHE components are mobility, aerobic, balance, resistance, and flexibility home-based exercises, supervised by video call. The primary study outcome is cancer-related fatigue. The secondary outcomes are quality of life, symptoms of depression and anxiety, physical activity level, cancer-related cognitive impairment, and functional capacity. Other outcomes are adherence to interventions and a follow-up questionnaire evaluating the individual perception in motivation, lifestyle changes, and main barriers to participation. All outcomes will be remotely assessed before and after intervention. Our analysis will follow the intention-to-treat approach and per-protocol criteria, with additional sub-group analysis. DISCUSSION: To our knowledge, this is the first randomized clinical trial in breast cancer patients using a face-to-face videoconference strategy to supervise physical exercise. Our hypothesis is of superiority for the effects of MTHE on primary and secondary outcomes compared to the effects of only the health education intervention.

trial registrationAdaptations to Breast Cancer and Exercise Using Telehealth (ABRACE: Telehealth), NCT04641377. Registered on 23 November 2021, https://clinicaltrials.gov/ct2/show/NCT04641377.

Indexed as

Breast NeoplasmsTelemedicineExerciseExercise TherapyFemaleHealth EducationHumansQuality of LifeRandomized Controlled Trials as TopicBreast neoplasmsDigital interventionFatiguemHealthMobile healthPhysical exerciseResistance trainingTelehealthTelemedicineTelerehabilitation

Identifiers

PMID36658611
PMCPMC9851110
OpenAlexW4317435975

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.