Evidence map›Paper›PMID 36658557›Full record

ArticleJournal of orthopaedic surgery and research2023

Biomechanical effects of hybrid constructions in the treatment of noncontinuous cervical spondylopathy: a finite element analysis.

Xiangyao Sun, Qingming Zhang, Li Cao, Juyong Wang, Jiang Huang, Yuqi Liu, Yang Zhang, Zelong Song, Wei Tang, Yunqiang Chen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Xiangyao SunDepartment of Orthopaedics, Xuanwu Hospital Capital Medical University, Beijing, 100053, China. sun.xiang.yao@163.com.
Qingming ZhangDepartment of Orthopaedics, Xuanwu Hospital Capital Medical University, Beijing, 100053, China.
Li CaoDepartment of Orthopaedics, Xuanwu Hospital Capital Medical University, Beijing, 100053, China.
Juyong WangDepartment of Orthopaedics, Xuanwu Hospital Capital Medical University, Beijing, 100053, China.
Jiang HuangDepartment of Orthopaedics, Xuanwu Hospital Capital Medical University, Beijing, 100053, China.
Yuqi LiuDepartment of Emergency, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Yang ZhangDepartment of Orthopaedics, The Seventh Medical Center of PLA General Hospital, Beijing, 100191, China.
Zelong SongNankai University School of Medicine, Nankai University, Tianjin, 300071, China.
Wei TangBeijing Glitzern Technology Co., Ltd, Beijing, 100077, China.
Yunqiang ChenBeijing Glitzern Technology Co., Ltd, Beijing, 100077, China.
Siyuan SunDepartment of Interdisciplinary, Life Science, Purdue University, West Lafayette, IN, 47907, USA.
Shibao LuDepartment of Orthopaedics, Xuanwu Hospital Capital Medical University, Beijing, 100053, China. 15624967325@163.com.
Capital Medical University · CNChinese PLA General Hospital · CNNational Clinical Research Center for Digestive Diseases · CNPurdue University West Lafayette · US

Funding

Beijing Hospitals Authority Youth Programme QML20210805Beijing Key Laboratory of Applied Biomechanics Research Open Project in 2022 2022KF03National Natural Youth Cultivation Program of 2021 in Xuanwu Hospital Capital Medical University QNPY2021018Research And Cultivation Fund of Capital Medical University 1220010144
6 · The paper itself

Abstract

backgroundHybrid construction (HC) may be an ideal surgical strategy than noncontinuous total disc replacement (TDR) and noncontinuous anterior cervical discectomy and fusion (ACDF) in the treatment of noncontinuous cervical spondylopathy. However, there is still no consensus on the segmental selection for ACDF or TDR in HC. The study aims to analyse the effects of different segment selection of TDR and ACDF on cervical biomechanical characteristics after HC surgery.

methodsTwelve FEMs of C2-C7 were constructed based on CT images of 12 mild cervical spondylopathy volunteers. Two kinds of HC were introduced in our study: Fusion-arthroplasty group (Group 1), upper-level (C3/4) ACDF, and lower-level TDR (C5/6); Arthroplasty-fusion group (Group 2), upper-level (C3/4) TDR and lower-level ACDF (C5/6). The follow-load technique was simulated by applying an axial initial load of 73.6 N through the motion centre of FEM. A bending moment of 1.0 Nm was applied to the centre of C2 in all FEMs. Statistical analysis was carried out by SPSS 26.0. The significance threshold was 5% (P < 0.05).

resultsIn the comparison of ROMs between Group 1 and Group 2, the ROM in extension (P = 0.016), and lateral bending (P = 0.038) of C4/5 were significantly higher in Group 1 group. The average intervertebral disc pressures at C2/3 in all directions were significantly higher in Group 1 than those in Group 2 (P < 0.005). The average contact forces in facet joints of C2/3 (P = 0.007) were significantly more than that in Group 2; however, the average contact forces in facet joints of C6/7 (P < 0.001) in Group 1 group were significantly less than that in Group 2.

conclusionsArthroplasty-fusion is preferred for intervertebral disc degeneration in adjacent upper segments. Fusion-arthroplasty is preferred for patients with lower intervertebral disc degeneration or lower posterior column degeneration.

trial registrationThis research was registered in Chinese Clinical Trial Registry (ChiCTR1900020513).

Indexed as

Intervertebral DiscIntervertebral Disc DegenerationSpinal FusionBiomechanical PhenomenaCervical VertebraeDiskectomyFinite Element AnalysisHumansRange of Motion, ArticularAnterior cervical discectomy and fusionBiomechanicsHybrid constructionNoncontinuous cervical spondylopathyTotal disc replacement

Identifiers

PMID36658557
PMCPMC9854215
OpenAlexW4317490373

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.