Evidence map›Paper›PMID 36658555›Full record

ArticleJournal of nanobiotechnology2023

Orally administration of cerium oxide nanozyme for computed tomography imaging and anti-inflammatory/anti-fibrotic therapy of inflammatory bowel disease.

Yameng Cao, Kai Cheng, Mei Yang, Zhichao Deng, Yana Ma, Xiangji Yan, Yuanyuan Zhang, Zhenzhen Jia, Jun Wang, Kangsheng Tu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 110 citations in OpenAlex.

  1. Article
  2. Review
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  7. Multifunctional Cu-doped MnMaterials today. Bio · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Biomedical Applications of Nanozymes: An Enzymology Perspective.Angewandte Chemie (International ed. in English) · 2025
    Review
  14. Review
  15. Electron-injected Pd@CeOJournal of nanobiotechnology · 2025
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Yameng CaoDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xian Jiaotong University, Xi'an, 710061, Shaanxi, China.
Kai ChengBritton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics - Hubei Bioinformatics & Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, Hubei, China.
Mei YangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xian Jiaotong University, Xi'an, 710061, Shaanxi, China.
Zhichao DengDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xian Jiaotong University, Xi'an, 710061, Shaanxi, China.
Yana MaDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xian Jiaotong University, Xi'an, 710061, Shaanxi, China.
Xiangji YanDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xian Jiaotong University, Xi'an, 710061, Shaanxi, China.
Yuanyuan ZhangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xian Jiaotong University, Xi'an, 710061, Shaanxi, China.
Zhenzhen JiaDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xian Jiaotong University, Xi'an, 710061, Shaanxi, China.
Jun WangDepartment of Emergency and Critical Care Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Kangsheng TuDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xian Jiaotong University, Xi'an, 710061, Shaanxi, China. tks0912@foxmail.com.
Jie LiangXijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710068, Shaanxi, China. liangjie@fmmu.edu.cn.
Mingzhen ZhangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xian Jiaotong University, Xi'an, 710061, Shaanxi, China. mzhang21@xjtu.edu.cn.
First Affiliated Hospital of Xi'an Jiaotong University · CNXi'an Jiaotong University · CNWuhan National Laboratory for Optoelectronics · CNXijing Hospital · CN

Funding

the National Natural Science Foundation of China 82000523
6 · The paper itself

Abstract

backgroundInflammatory bowel disease (IBD) is a chronic nonspecific disease with unknown etiology. Currently, the anti-inflammatory therapeutic approaches have achieved a certain extent of effects in terms of inflammation alleviation. Still, the final pathological outcome of intestinal fibrosis has not been effectively improved yet.

resultsIn this study, dextran-coated cerium oxide (D-CeO

conclusionWe introduced cerium oxide nanozyme as a novel therapeutic approach with computed tomography (CT)-guided anti-inflammatory and anti-fibrotic therapy for the management of IBD. Collectively, without appreciable systemic toxicity, D-CeO

Indexed as

CeriumInflammatory Bowel DiseasesAnti-Inflammatory AgentsAntioxidantsCytokinesFibrosisHumansHydrogen PeroxideInflammationReactive Oxygen SpeciesTomographyTomography, X-Ray ComputedAnti-Inflammatory AgentsAntioxidantsceric oxideCeriumCytokinesHydrogen PeroxideReactive Oxygen SpeciesCerium oxide nanozymeCT imagingInflammationInflammatory bowel diseaseIntestinal fibrosis

Identifiers

PMID36658555
PMCPMC9854161
OpenAlexW4317436914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.