Evidence map›Paper›PMID 36658486›Full record

ArticleBMC microbiology2023

Local characteristics of molecular epidemiolgy of Acinetobacter baumannii in Jilin province (northeast China).

Qingsong You, Xue Du, Nannan Hu, Yusi Zhang, Na Zhang, Fusheng Wang, Jinghua Li, Yanbo Sun, Fang Wang, Hongyan Shi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Qingsong YouDepartment of Pathogenobiology, CollegeofBasicMedicalScience, Jilin University, 126, Xinmin Street, Changchun, 130021, Jilin, China.
Xue DuAffiliated Hospital of Changchun University of Chinese Medicine, 1478, Gongnong Avenues, Changchun, China.
Nannan HuDepartment of Pathogenobiology, CollegeofBasicMedicalScience, Jilin University, 126, Xinmin Street, Changchun, 130021, Jilin, China.
Yusi ZhangDepartment of Pathogenobiology, CollegeofBasicMedicalScience, Jilin University, 126, Xinmin Street, Changchun, 130021, Jilin, China.
Na ZhangDepartment of Pathogenobiology, CollegeofBasicMedicalScience, Jilin University, 126, Xinmin Street, Changchun, 130021, Jilin, China.
Fusheng WangDepartment of Pathogenobiology, CollegeofBasicMedicalScience, Jilin University, 126, Xinmin Street, Changchun, 130021, Jilin, China.
Jinghua LiDepartment of Pathogenobiology, CollegeofBasicMedicalScience, Jilin University, 126, Xinmin Street, Changchun, 130021, Jilin, China.
Yanbo SunDepartment of Pathogenobiology, CollegeofBasicMedicalScience, Jilin University, 126, Xinmin Street, Changchun, 130021, Jilin, China.
Fang WangDepartment of Pathogenobiology, CollegeofBasicMedicalScience, Jilin University, 126, Xinmin Street, Changchun, 130021, Jilin, China.
Hongyan ShiDepartment of Pathogenobiology, CollegeofBasicMedicalScience, Jilin University, 126, Xinmin Street, Changchun, 130021, Jilin, China. hyshi@jlu.edu.cn.
Jilin University · CNChangchun University of Chinese Medicine · CN

Funding

Fundation of Education Department of Jilin Province JJKH20201042KJ
6 · The paper itself

Abstract

A. Baumannii is an opportunistic nosocomial pathogen which has severe antibiotic resistance. However, the epidemiology is less clearly understood in Jilin province and China. Thus, 89 A. baumannii isolates from a single hospital in Jilin province between 2013-2017 were performed by MLST. In order to better understanding of the epidemiology of Jilin isolates, Chinese strains originated from other domestic regions and worldwide isolates in MLST database were analyzed by silico phylogenetic tools together. A total of 22 STs in Jilin were identified, and 10 STs were found to be novel. The top three predominant sequence types are ST195 (n = 34, 38.2%), ST208 (n = 14, 15.7%) and ST540 (n = 13, 14.6%). ST369 is predicted to be group founder and ST195, ST540 are subgroup founders of the majority STs in Jilin Province. Some newly discovered singletons showed close relationship with strains from other countries, which suggest that nation-cross transmission is one of important origin of Jilin strains. The majority of Jilin STs showed clonality and close relationship with the majorities from other regions of China. But occupation of individual STs in Jilin were different from that of other domestic regions. The aggregation trend and genetic relationship proved that predominant Jilin STs continue to mutate during transmission. Drug resistance facilitated transmission of Jilin A.baumannii isolates because more than 94% of isolates are resistant to at least one carbapenem and the STs with strong resistance to carbapenems usually has more isolates. In conclusion, high diversity and different occupation of STs, and occupation of novel STs proved that epidemiology of A. baumannii in Jilin has special regional characteristics, and drug resistance facilitated transmission of domestic strains and foreign strains.

Indexed as

Acinetobacter baumanniiAnti-Bacterial Agentsbeta-LactamasesCarbapenemsChinaMicrobial Sensitivity TestsMolecular EpidemiologyMultilocus Sequence TypingPhylogenyAnti-Bacterial Agentsbeta-LactamasesCarbapenemsAcinetobacter baumanniiAntibiotic resistanceEpidemiologyGeographic regionMulti-locus sequence typingPhylogeny

Identifiers

PMID36658486
PMCPMC9850558
OpenAlexW4317399326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.