Trial reportJournal of neuro-oncology2023
Carer preparedness improved by providing a supportive educational intervention for carers of patients with high-grade glioma: RCT results.
Trial report in Journal of neuro-oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Caring for the Informal Caregivers: Systematic Review of Unmet Needs in Palliative Care.Nursing open · 2025Pooled it
- Web-Based Psychoeducational Intervention to Improve Family Caregiver Preparedness in Specialized Palliative Home Care: A Randomized Controlled Trial.Psycho-oncology · 2025Trial
- Current and bereaved caregivers' experiences of participating in the adapted Telehealth Making Sense of Brain Tumour program in the context of high-grade glioma.Neuro-oncology practice · 2026Article
- The CARING intervention for neuro-oncology family caregivers: Primary outcomes from an abbreviated randomized controlled trial.Neuro-oncology practice · 2026Article
- Facilitators and Barriers of Relatives' Involvement in Care of Patients With Acquired Brain Injury or Malignant Brain Tumour: Scoping Review.Nursing open · 2026Article
- Group-based interventions for caregivers to patients diagnosed with a brain tumor: A systematic review.Neuro-oncology practice · 2025Article
- Nurse-identified needs, recommendations, and referrals during consultations with family carers of patients diagnosed with high-grade glioma.Neuro-oncology practice · 2025Article
- Understanding Health Information Needs: An Evaluation of Co-Design Video-Assisted Education.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025Article
- Identifying components of care coordination for primary brain tumor: A scoping review.Neuro-oncology practice · 2025Review
- Out-of-pocket costs for patients diagnosed with high-grade glioma and their carers.Neuro-oncology practice · 2025Article
- The relationship between proxy decision-making content and cues by families of patients with malignant brain tumor: A descriptive qualitative study.International journal of nursing sciences · 2025Article
- Interventions facilitating the involvement of relatives of patients with acquired brain injury or malignant brain tumour: A scoping review.Journal of clinical nursing · 2025Article
- Reporting standards in randomized controlled trials involving neuro-oncology caregivers: A systematic review report from the RANO-Cares working group.Neuro-oncology practice · 2025Article
- Development of a brief screening measure of unmet supportive care needs (SCNS-P&C-6) in caregivers of people with high-grade glioma.Journal of patient-reported outcomes · 2025Article
- Glioblastoma Patient and Caregiver Perspectives of Treatment Side-Effects and Information Provision.Journal of patient experience · 2025Article
- A nurse-led intervention for carers of people with high-grade glioma: A case series of carers reporting high distress.Neuro-oncology practice · 2024Article
- The impact of a primary brain tumor diagnosis on caregivers: Insights from the patients' perspective.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- What do carers of people with high-grade glioma perceive could improve their preparedness to care, and what additional support do they require?Neuro-oncology practice · 2024Article
- Exploratory multi-methods evaluation of an online intervention for carers of people with high-grade glioma.Neuro-oncology practice · 2023Article
- Paving the way to evidence-based clinical practice: Establishing effective caregiver and family support interventions.Neuro-oncology practice · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 8 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHigh-grade glioma (HGG) is a rapidly progressing and debilitating disease. Family carers take on multiple responsibilities and experience high levels of distress. We aimed to deliver a nurse-led intervention (Care-IS) to carers to improve their preparedness to care and reduce distress.
methodsWe conducted a randomised controlled trial (ACTRN:12612001147875). Carers of HGG patients were recruited during patients' combined chemoradiation treatment. The complex intervention comprised four components: (1) initial telephone assessment of carer unmet needs; (2) tailored hard-copy resource folder; (3) home visit; and, (4) monthly telephone support for up to 12 months. Primary outcomes included preparedness for caregiving and distress at 2, 4, 6 and 12 months. Intervention effects were estimated using linear mixed models which included a time by group interaction. Secondary outcomes included anxiety, depression, quality of life, carer competence and strain.
resultsWe randomised 188 carers (n = 98 intervention, n = 90 control). The intervention group reported significantly higher preparedness for caregiving at 4 months (model β = 2.85, 95% CI 0.76-4.93) and all follow-up timepoints including 12 months (model β = 4.35, 95% CI 2.08-6.62), compared to the control group. However, there was no difference between groups in carer distress or any secondary outcomes.
conclusionsThis intervention was effective in improving carer preparedness. However, carer distress was not reduced, potentially due to the debilitating/progressive nature of HGG and ongoing caring responsibilities. Future research must explore whether carer interventions can improve carer adjustment, self-efficacy and coping and how we support carers after bereavement. Additionally, research is needed to determine how to implement carer support into practice.
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