ArticleAnnals of surgical oncology2023
Symptom Trajectories Informing Patient Care After Lung Cancer Surgery: A Longitudinal Patient-Reported Outcome Study.
Article in Annals of surgical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 32 citations in OpenAlex.
- Patient perspectives on electronic patient-reported outcome-based symptom management after lung cancer surgery: a qualitative study.Journal of patient-reported outcomes · 2026Trial
- Factors Influencing Symptom Severity at Discharge after Lobectomy and Sublobar Resection Through Video-assisted Thoracoscopic Surgery.Interdisciplinary cardiovascular and thoracic surgery · 2025Trial
- Electronic Patient-Reported Outcome-Based Symptom Management Versus Usual Care After Lung Cancer Surgery: Long-Term Results of a Multicenter, Randomized, Controlled Trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024Trial
- Patient-reported outcomes with a personalized follow-up program after lung cancer resection: A single-center randomized controlled trial.Asia-Pacific journal of oncology nursing · 2026Article
- Dyspnea and cough trajectories in older adults (aged 60-80 years) after lung cancer surgery: a 6-month longitudinal study.BMC geriatrics · 2026Article
- Evaluating test-retest reliability of patient-reported outcome measures in cancer patients: a protocol for a methodological systematic review.Systematic reviews · 2026Article
- Symptom Cluster Trajectories of Cough, Shortness of Breath, and Disturbed Sleep in Patients Undergoing Lung Cancer Surgery: A Longitudinal Study.Annals of surgical oncology · 2026Article
- Expanding Surgical Boundaries in Pseudomyxoma Peritonei: The Emerging Role of Cytoreductive Surgery and Hyperthermic Intrathoracic Chemotherapy for Pleural Metastases.Annals of surgical oncology · 2026Article
- Article
- Postoperative symptom trajectories in early-stage lung cancer: a latent transition analysis.Surgical endoscopy · 2026Article
- The Symptom Clusters and Core Symptoms in Patients with Lung Cancer After Surgery: A Longitudinal Network Analysis.Patient preference and adherence · 2026Article
- Symptom Network Evolution and Longitudinal Interrelationships in Early-Stage Lung Cancer Patients Postoperatively.International journal of general medicine · 2026Article
- Early Post-discharge Pain Trajectories After Thoracoscopic Sublobar Resection for Stage IA Non-small Cell Lung Cancer.Annals of surgical oncology · 2026Observational
- Patient-reported outcomes of radiofrequency ablation-video-assisted thoracoscopic surgery (VATS) hybrid surgeryTranslational lung cancer research · 2025Article
- Evidence summary on pain management in thoracoscopic lung cancer surgery.Asia-Pacific journal of oncology nursing · 2025Review
- A score prediction model for predicting the heterogeneity symptom trajectories among lung cancer patients during perioperative period: a longitudinal observational study.Annals of medicine · 2025Observational
- Electronic patient-reported outcomes for outpatient care after non-intubated thoracic surgery in early-stage lung cancer.Journal of thoracic disease · 2025Article
- Quality of life in older adults (aged 60-80 years) after lung cancer surgery: a longitudinal observational study.Health and quality of life outcomes · 2025Observational
- Longitudinal Trajectory of Patient-Reported Fatigue in Patients Undergoing Thoracoscopic Lung Cancer Surgery.Annals of surgical oncology · 2025Article
- Predictive relationship in perioperative symptoms and step count for lung cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundApplication of patient-reported outcomes (PROs) in surgical oncology has been limited because of patient heterogeneity. We analyzed symptom trajectories and their associations with recovery outcomes after lung cancer surgery, aiming to profile the heterogeneity of patients' experiences and to identify patients needing extensive care.
methodsSymptoms were assessed with the MDASI-LC before surgery, daily after surgery in hospital and weekly within 1 month after discharge. Patients were clustered based on symptoms from post-operative day 1 (POD1) to POD5, using the latent-class-trajectory-model. Functional recovery was compared across the trajectories. Logistic regression was used to explore risk factors for trajectories of more severe symptoms.
resultsBased on the five most severe post-surgery symptoms (pain, fatigue, coughing, shortness of breath, and disturbed sleep), we identified three distinct symptom trajectories among 424 patients [mild, N = 225 (53.07%); severe-to-mild, N = 86 (20.28%); severe, N = 104 (24.53%)]. At discharge, more 'severe' patients (73.96%) did not achieve a functional recovery compared with those in mild (32.54%, P < 0.0001) or severe-to-mild (56.96%, P = 0.0274) groups. Factors of significant symptom increase on POD1 were younger-than-55 (OR = 1.94 [95% CI 1.30-2.93], P = 0.001), undergoing open or multi-port video-assisted thoracoscopic surgery (OR = 1.59 [95% CI 1.05-2.41], P = 0.03), and using two chest tubes (OR = 1.72 [95% CI 1.12-2.65], P = 0.01). For patients experiencing dramatic symptom increase on POD1, older age (OR = 2.51 [95% CI 1.40-4.59], P = 0.002) was associated with 'severe' trajectory.
conclusionsThis study demonstrated that PRO measures were capable of profiling heterogeneous symptom trajectories after lung cancer surgery. Those in-hospital trajectories were able to differentiate patients' responses to treatments and signal the needs for extensive post-discharge care.
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