Evidence map›Paper›PMID 36658178›Full record

ArticleScientific reports2023

Breaking the tight genetic linkage between the a1 and sh2 genes led to the development of anthocyanin-rich purple-pericarp super-sweetcorn.

Apurba Anirban, Alice Hayward, Hung T Hong, Ardashir Kharabian Masouleh, Robert J Henry, Tim J O'Hare

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Temporal expression of3 Biotech · 2025
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Apurba AnirbanCentre for Nutrition and Food Sciences, Queensland Alliance for Agriculture & Food Innovation (QAAFI), The University of Queensland, Brisbane, Australia. apurba.anirban@bot.jnu.ac.bd.
Alice HaywardCentre for Horticulture Science, QAAFI, The University of Queensland, Brisbane, Australia.
Hung T HongCentre for Nutrition and Food Sciences, Queensland Alliance for Agriculture & Food Innovation (QAAFI), The University of Queensland, Brisbane, Australia.
Ardashir Kharabian MasoulehCentre for Crop Science, QAAFI, The University of Queensland, Brisbane, Australia.
Robert J HenryCentre for Crop Science, QAAFI, The University of Queensland, Brisbane, Australia.
Tim J O'HareCentre for Nutrition and Food Sciences, Queensland Alliance for Agriculture & Food Innovation (QAAFI), The University of Queensland, Brisbane, Australia.
The University of Queensland · AUAgriculture and Food · AUARC Centre of Excellence for Plant Success in Nature and Agriculture · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The existence of purple-pericarp super-sweetcorn based on the supersweet mutation, shrunken2 (sh2), has not been previously reported, due to its extremely tight genetic linkage to a non-functional anthocyanin biosynthesis gene, anthocyaninless1 (a1). Generally, pericarp-pigmented starchy purple corn contains significantly higher anthocyanin. The development of purple-pericarp super-sweetcorn is dependent on breaking the a1-sh2 tight genetic linkage, which occurs at a very low frequency of < 1 in 1000 meiotic crossovers. Here, to develop purple-pericarp super-sweetcorn, an initial cross between a male purple-pericarp maize, 'Costa Rica' (A1Sh2.A1Sh2) and a female white shrunken2 super-sweetcorn, 'Tims-white' (a1sh2.a1sh2), was conducted. Subsequent self-pollination based on purple-pericarp-shrunken kernels identified a small frequency (0.08%) of initial heterozygous F3 segregants (A1a1.sh2sh2) producing a fully sh2 cob with a purple-pericarp phenotype, enabled by breaking the close genetic linkage between the a1 and sh2 genes. Resulting rounds of self-pollination generated a F6 homozygous purple-pericarp super-sweetcorn (A1A1.sh2sh2) line, 'Tim1'. Genome sequencing revealed a recombination break between the a1 and yz1 genes of the a1-yz1-x1-sh2  multigenic interval. The novel purple-pericarp super-sweetcorn produced a similar concentration of anthocyanin and sugar as in its purple-pericarp maize and white super-sweetcorn parents, respectively, potentially adding a broader range of health benefits than currently exists with standard yellow/white sweetcorn.

Indexed as

AnthocyaninsZea maysChromosome MappingGenes, PlantPhenotypeAnthocyanins

Identifiers

PMID36658178
PMCPMC9852272
OpenAlexW4317435521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.