ArticleNature communications2023
Phylogeography and transmission of Mycobacterium tuberculosis spanning prisons and surrounding communities in Paraguay.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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Who cites it
22 citing papers in PubMed.
- Comparison of phylogenetic metrics of transmission between symptomatic and asymptomatic tuberculosis in individuals who were incarcerated in Brazil in 2008-24: a retrospective genomic epidemiology study.The Lancet. Microbe · 2026Article
- Comparative evaluation of three commercial real-time PCR kits for direct detection ofMicrobiology spectrum · 2026Article
- Systematic review of the tuberculosis burden in prisons: Regional patterns and gaps in Latin America and the Caribbean.Global epidemiology · 2026Review
- Drug-Resistant Tuberculosis in Prisons of Latin America and the Caribbean: A Critical Reflection on Structural Challenges and Gaps.Tropical medicine and infectious disease · 2026Review
- Tuberculosis in prisons: an integrated prevention and care cascade for a persistent structural epidemic.Frontiers in public health · 2026Review
- Comparison of phylogenetic metrics of transmission in symptomatic and asymptomatic tuberculosis.medRxiv : the preprint server for health sciences · 2025Article
- The concentration of tuberculosis within Paraguay's Indigenous population, 2018-2022: a retrospective population-based study.Lancet regional health. Americas · 2025Article
- Transmission ofEpidemiology and infection · 2025Article
- Global epidemiology of Mycobacterium tuberculosis lineage 4 insights from Ecuadorian genomic data.Scientific reports · 2025Article
- Signatures of transmission in within-host Mycobacterium tuberculosis complex variation: a retrospective genomic epidemiology study.The Lancet. Microbe · 2025Article
- Mass incarceration as a driver of the tuberculosis epidemic in Latin America and projected effects of policy alternatives: a mathematical modelling study.The Lancet. Public health · 2024Article
- Whole genome sequencing analysis of Mycobacterium tuberculosis reveals circulating strain types and drug-resistance mutations in the Philippines.Scientific reports · 2024Article
- Mass incarceration as a driver of the tuberculosis epidemic in Latin America and projected impacts of policy alternatives: A mathematical modeling study.medRxiv : the preprint server for health sciences · 2024Article
- Genomic evolution of ST228 SCCmec-I MRSA 10 years after a major nosocomial outbreak.Journal of clinical microbiology · 2024Article
- SpecificMicroorganisms · 2024Article
- Prison as a driver of recent transmissions of multidrug-resistant tuberculosis in Callao, Peru: a cross-sectional study.Lancet regional health. Americas · 2024Article
- Excess tuberculosis risk during and following incarceration in Paraguay: a retrospective cohort study.Lancet regional health. Americas · 2024Article
- Incarceration and TB: the epidemic beyond prison walls.BMJ global health · 2024Article
- Enduring Injustice: Infectious Disease Outbreaks in Carceral Settings.The Journal of infectious diseases · 2024Article
- Rapid and accurate identification and differentiation ofFrontiers in public health · 2024Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
Recent rises in incident tuberculosis (TB) cases in Paraguay and the increasing concentration of TB within prisons highlight the urgency of targeting strategies to interrupt transmission and prevent new infections. However, whether specific cities or carceral institutions play a disproportionate role in transmission remains unknown. We conducted prospective genomic surveillance, sequencing 471 Mycobacterium tuberculosis complex genomes, from inside and outside prisons in Paraguay's two largest urban areas, Asunción and Ciudad del Este, from 2016 to 2021. We found genomic evidence of frequent recent transmission within prisons and transmission linkages spanning prisons and surrounding populations. We identified a signal of frequent M. tuberculosis spread between urban areas and marked recent population size expansion of the three largest genomic transmission clusters. Together, our findings highlight the urgency of strengthening TB control programs to reduce transmission risk within prisons in Paraguay, where incidence was 70 times that outside prisons in 2021.
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