Evidence map›Paper›PMID 36657981›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2023

Molecular Imaging of Pulmonary Inflammation in Users of Electronic and Combustible Cigarettes: A Pilot Study.

Reagan R Wetherill, Robert K Doot, Anthony J Young, Hsiaoju Lee, Erin K Schubert, Corinde E Wiers, Frank T Leone, Robert H Mach, Henry R Kranzler, Jacob G Dubroff

Open access · hybridAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. E-Cigarette or Vaping Product Use-Associated Lung Injury: A Comprehensive Review.International journal of environmental research and public health · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Electronic Cigarette Harms: Aggregate Evidence Shows Damage to Biological Systems.International journal of environmental research and public health · 2023
    Review
  11. Reply: Molecular Imaging of Pulmonary Inflammation: Claiming That Vaping Is More Harmful Than Smoking Is Unsupported.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  12. Molecular Imaging of Pulmonary Inflammation: Claiming That Vaping Is More Harmful Than Smoking Is Unsupported.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  13. [Cells · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Reagan R WetherillDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; rweth@pennmedicine.upenn.edu.
Robert K DootDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Anthony J YoungDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Hsiaoju LeeDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Erin K SchubertDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Corinde E WiersDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Frank T LeoneComprehensive Smoking Treatment Program, Penn Lung Center, Philadelphia, Pennsylvania; and.
Robert H MachDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Henry R KranzlerDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Jacob G DubroffDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
University of Pennsylvania · US

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
Radiochemistry CoreP30DA046345 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI MACH, ROBERT H · 2019 to 2023
$9.4M
Using PET to Measure Pulmonary Oxidative Stress in E-cigarette UsersR21HL144673 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WETHERILL, REAGAN R · 2019 to 2020
$604k
NCATS NIH HHS UL1 TR001878NHLBI NIH HHS R21 HL144673NIDA NIH HHS P30 DA046345
6 · The paper itself

Abstract

Electronic cigarette (EC) use has increased dramatically, particularly among adolescents and young adults, and, like cigarette use, can cause pulmonary inflammation and increase the risk of lung disease.

Indexed as

Electronic Nicotine Delivery SystemsPneumoniaTobacco ProductsAdolescentElectronicsHumansInflammationMolecular ImagingNitric Oxide Synthase Type IIPilot ProjectsYoung AdultNitric Oxide Synthase Type II18F-NOScigaretteselectronic cigarettesinflammationPET

Identifiers

PMID36657981
PMCPMC10152129
OpenAlexW4317495282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.