Evidence map›Paper›PMID 36657951›Full record

ArticleAJNR. American journal of neuroradiology2023

Early Fetal Corpus Callosum: Demonstrating Normal Growth and Detecting Pathologies in Early Pregnancy.

T Weissbach, A Massarwa, E Hadi, S Lev, A Haimov, E Katorza, A Brenner-Weissmann, E Krampl-Bettelheim, G Kasprian, R Sharon and 4 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

T WeissbachFrom The Institute of Obstetrical and Gynecological Imaging (T.W., A.M., E.H., E. Katorza, A.B.-W., R.A., B.W., E. Kassif) Ferbyt@gmail.com.ORCID 0000-0001-5558-7871
A MassarwaFrom The Institute of Obstetrical and Gynecological Imaging (T.W., A.M., E.H., E. Katorza, A.B.-W., R.A., B.W., E. Kassif).
E HadiFrom The Institute of Obstetrical and Gynecological Imaging (T.W., A.M., E.H., E. Katorza, A.B.-W., R.A., B.W., E. Kassif).ORCID 0000-0002-5678-6802
S LevDepartment of Obstetrics and Gynecology (S.L., A.H.).ORCID 0000-0002-2116-0973
A HaimovDepartment of Obstetrics and Gynecology (S.L., A.H.).
E KatorzaFrom The Institute of Obstetrical and Gynecological Imaging (T.W., A.M., E.H., E. Katorza, A.B.-W., R.A., B.W., E. Kassif).ORCID 0000-0003-4225-7421
A Brenner-WeissmannFrom The Institute of Obstetrical and Gynecological Imaging (T.W., A.M., E.H., E. Katorza, A.B.-W., R.A., B.W., E. Kassif).ORCID 0000-0003-0908-2068
E Krampl-BettelheimDepartment of Obstetrics and Gynecology (E.K.-B.).ORCID 0000-0002-3590-6414
G KasprianDepartment of Biomedical Imaging and Image-Guided Therapy (G.K.), Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-3858-3347
R SharonDepartment of Neurology (R.S.), Sheba Medical Center, Tel Hashomer, Israel.ORCID 0000-0002-2452-8921
R AchironFrom The Institute of Obstetrical and Gynecological Imaging (T.W., A.M., E.H., E. Katorza, A.B.-W., R.A., B.W., E. Kassif).ORCID 0000-0002-8294-3672
B WeiszFrom The Institute of Obstetrical and Gynecological Imaging (T.W., A.M., E.H., E. Katorza, A.B.-W., R.A., B.W., E. Kassif).ORCID 0000-0003-1606-452X
Z KivilevitchWomen's Ultrasound Unit (Z.K.), Maccabi Health Services, Negev Medical Center, Beer-Sheva, Israel.ORCID 0000-0002-3265-408X
E KassifFrom The Institute of Obstetrical and Gynecological Imaging (T.W., A.M., E.H., E. Katorza, A.B.-W., R.A., B.W., E. Kassif).ORCID 0000-0002-2201-9461
Tel Aviv University · ILMaccabi Healthcare Services · ILMedical University of Vienna · ATUniversity Radiology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeA malformed corpus callosum carries a risk for abnormal neurodevelopment. The advent of high-frequency transducers offers the opportunity to assess corpus callosum development in early pregnancy. The aim of the study was to construct a reference chart of the fetal corpus callosum length on ultrasound between 13 and 19 weeks of gestation and to prospectively examine growth patterns in pathologic cases. MATERIALS AND

methodsWe performed a prospective cross-sectional study between 2020 and 2022 in well-dated, low-risk, singleton pregnancies between 13 and 19 weeks of gestation. A standardized image was obtained in the midsagittal plane. Imaging criteria were used as a confirmation of the early corpus callosum. Measurements were taken by 4 trained sonographers. Intra- and interobserver variability was assessed. Corpus callosum length in centiles were calculated for each gestational week.

resultsOne hundred eighty-seven fetuses were included in the study. All cases met inclusion criteria. At 13 weeks of gestation, the margins of the early corpus callosum were sufficiently clear to be measured in 80% (20/25) of fetuses. A cubic polynomial regression model best described the correlation between corpus length and gestational age. The correlation coefficient (

conclusionsProvided is a nomogram of the early fetal corpus callosum. Applying imaging criteria helped to identify a case of complete agenesis of the corpus callosum as early as 14 weeks.

Indexed as

Corpus CallosumUltrasonography, PrenatalAgenesis of Corpus CallosumCross-Sectional StudiesFemaleFetusGestational AgeHumansPregnancyProspective Studies

Identifiers

PMID36657951
PMCPMC9891336
OpenAlexW4317433567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.