Evidence map›Paper›PMID 36657950›Full record

ArticleAJNR. American journal of neuroradiology2023

Reliability of Functional and Diffusion MR Imaging Near Cerebral Cavernous Malformations.

M Colasurdo, H Chen, R Navarra, E Piccirilli, A Delli Pizzi, V Panara, M Caulo

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PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M ColasurdoFrom the Departments of Neuroscience, Imaging and Clinical Sciences (M.C., R.N., E.P., V.P., M.C.) Italymcolasurdo@gmail.com.ORCID 0000-0002-7823-3088
H ChenNational Institutes of Health (H.C.), Bethesda, Maryland.ORCID 0000-0003-2455-748X
R NavarraFrom the Departments of Neuroscience, Imaging and Clinical Sciences (M.C., R.N., E.P., V.P., M.C.).ORCID 0000-0003-2520-1530
E PiccirilliFrom the Departments of Neuroscience, Imaging and Clinical Sciences (M.C., R.N., E.P., V.P., M.C.).ORCID 0000-0003-3105-1292
A Delli PizziInnovative Technologies in Medicine & Dentistry (A.D.P.), G. D'Annunzio University of Chieti, Pescara, Chieti, Italy.ORCID 0000-0002-2011-3753
V PanaraFrom the Departments of Neuroscience, Imaging and Clinical Sciences (M.C., R.N., E.P., V.P., M.C.).ORCID 0000-0001-9655-3926
M CauloFrom the Departments of Neuroscience, Imaging and Clinical Sciences (M.C., R.N., E.P., V.P., M.C.).ORCID 0000-0002-4507-2740

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeSurgical resection of cerebral cavernous malformations close to eloquent regions frequently uses fMRI and DTI for surgical planning to best preserve neurologic function. This study investigates the reliability of fMRI and DTI near cerebral cavernous malformations. MATERIALS AND

methodsConsecutive patients with cerebral cavernous malformations undergoing presurgical fMRI and DTI mapping were identified. Each cerebral cavernous malformation was hand-contoured; 2 sequential 4-mm expansion shells (S1 and S2) were created, generating 2 ROIs and 2 contralateral controls. Fractional anisotropy and regional homogeneity measurements were then extracted from each ROI and compared with the contralateral controls. Reliability, accuracy, and precision were compared as appropriate.

resultsFifty-four patients were identified and included. Errors of fractional anisotropy were significantly lower than those of regional homogeneity in S1 and S2 (

conclusionsOur findings suggest that hemosiderin-rich lesions such as cerebral cavernous malformations may lead to artifactual depression of fMRI signals and that clinicians and surgeons should interpret fMRI studies near cerebral cavernous malformations with caution. While fMRI is considerably affected by cerebral cavernous malformation-related artifacts, DTI appears to be relatively unaffected and remains a reliable imaging technique near cerebral cavernous malformations.

Indexed as

Hemangioma, Cavernous, Central Nervous SystemHumansMagnetic Resonance ImagingPostoperative ComplicationsReproducibility of Results

Identifiers

PMID36657950
PMCPMC9891323

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.