Evidence map›Paper›PMID 36657819›Full record

ArticleBMJ case reports2023

Neonatal herpes simplex presenting as a zosteriform eruption.

Elizabeth Anderson, Emma Johns, Joseph Conlon, Ezzeldin Saleh

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Elizabeth AndersonInternal Medicine, Southern Illinois University School of Medicine, Springfield, Illinois, USA.
Emma JohnsDepartment of Pediatrics, Southern Illinois University School of Medicine, Springfield, Illinois, USA.
Joseph ConlonDepartment of Pediatrics and Department of Dermatology, Southern Illinois University School of Medicine, Springfield, Illinois, USA.
Ezzeldin SalehPediatrics-Infectious Diseases, Southern Illinois University School of Medicine, Springfield, Illinois, USA esaleh84@siumed.edu.ORCID http://orcid.org/0000-0001-9655-2376
Southern Illinois University School of Medicine · US

Funding

UC San Diego RAPID Faculty Development Program in Infectious DiseasesR25AI147376 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ADRIANA H TREMOULET, Joann Trejo · 2020 to 2026
$2.5M
NIAID NIH HHS R25 AI147376
6 · The paper itself

Abstract

Herpes simplex virus (HSV) infection in newborn infants is a potentially devastating disease leading to death and disability. Skin, eye and mouth (SEM) infections account for approximately half of the cases in the USA. The appearance of skin findings often guides clinicians towards early diagnosis of HSV infection, prompt interventions and life-saving management; however, less than half of neonates with proven disease present with characteristic vesicular lesions. Furthermore, if SEM infections are not treated promptly, there is significant risk of progression to central nervous system and disseminated disease. We present a case of HSV-2 infection in a neonate with an atypical zosteriform eruption on day 3 of life. This case demonstrates that neonatal HSV can unusually present in a zosteriform rash. By elucidating this unique presentation, we highlight atypical HSV skin presentation and emphasise on the importance of earlier diagnosis and antiviral treatment to prevent the associated morbidity and mortality.

Indexed as

ExanthemaHerpes SimplexInfant, Newborn, DiseasesPregnancy Complications, InfectiousAntiviral AgentsFemaleHumansInfantInfant, NewbornPregnancyAntiviral Agentsdermatologyinfectious diseasesneonatal and paediatric intensive care

Identifiers

PMID36657819
PMCPMC9853119
OpenAlexW4317500318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.