Evidence map›Paper›PMID 36657751›Full record

ArticleBMJ open2023

Cessation of smoking trial in the emergency department (CoSTED): protocol for a multicentre randomised controlled trial.

Caitlin Notley, Lucy Clark, Pippa Belderson, Emma Ward, Allan B Clark, Steve Parrott, Sanjay Agrawal, Ben M Bloom, Adrian A Boyle, Geraint Morris and 6 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04854616 (Cessation of Smoking Trial in the Emergency Department), which is not on this map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04854616 nacompletednot on this map

Cessation of Smoking Trial in the Emergency Department

TypeinterventionalSponsorNorfolk and Norwich University Hospitals NHS Foundation TrustRan2022 to 2023Enrolled972ConditionsSmoking Cessation, Electronic Cigarette Use, E-Cig Use, VapingArmsCoSTED Intervention
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2026
    Pooled it
  2. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2025
    Pooled it
  3. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2025
    Pooled it
  4. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2024
    Pooled it
  5. Cessation of Smoking Trial in the Emergency Department: Long-Term Follow-up of a Randomized Controlled Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Trial
  6. Trial
  7. Trial
  8. Trial
  9. Engagement With Stop Smoking Services After Referral or Signposting: A Mixed-Methods Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Trial
  10. Trial
  11. Trial
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Caitlin NotleyFaculty of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich, UK C.Notley@uea.ac.uk.ORCID 0000-0003-0876-3304
Lucy ClarkNorwich Clincial Trials Unit, Faculty of Medicine and Health Sciences, University of East Anglia, Norwich, UK.ORCID 0000-0001-7162-0512
Pippa BeldersonFaculty of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich, UK.
Emma WardFaculty of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich, UK.
Allan B ClarkNorwich Clincial Trials Unit, Faculty of Medicine and Health Sciences, University of East Anglia, Norwich, UK.
Steve ParrottDepartment of Health Sciences, University of York, York, UK.
Sanjay AgrawalInstitute of Lung Health, University of Leicester, Leicester, UK.
Ben M BloomEmergency Department, Barts Health NHS Trust, London, UK.
Adrian A BoyleEmergency Medicine, Addenbrooke's Hospital, Cambridge, UK.
Geraint MorrisDepartment of Emergency Medicine, Homerton University Hospital NHS Foundation Trust, London, UK.
Alasdair GrayDepartment of Emergency Medicine, Royal Infirmary of Edinburgh, Edinburgh, UK.
Tim CoatsDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Mei-See ManNorwich Clincial Trials Unit, Faculty of Medicine and Health Sciences, University of East Anglia, Norwich, UK.
Linda BauldUsher Institute of Population Health Sciences and Informatics, University of Edinburgh Division of Medical and Radiological Sciences, Edinburgh, UK.ORCID 0000-0001-7411-4260
Richard HollandMedical School, University of Leicester, Leicester, UK.
Ian PopeFaculty of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAttendees of emergency departments (EDs) have a higher than expected prevalence of smoking. ED attendance may be a good opportunity to prompt positive behaviour change, even for smokers not currently motivated to quit. This study aims to determine whether an opportunist smoking cessation intervention delivered in the ED can help daily smokers attending the ED quit smoking and is cost-effective. METHODS AND ANALYSIS: A two-arm pragmatic, multicentred, parallel-group, individually randomised, controlled superiority trial with an internal pilot, economic evaluation and mixed methods process evaluation. The trial will compare ED-based brief smoking cessation advice, including provision of an e-cigarette and referral to local stop smoking services (intervention) with the provision of contact details for local stop smoking services (control). Target sample size is 972, recruiting across 6 National Health Service EDs in England and Scotland. Outcomes will be collected at 1, 3 and 6 months. The primary outcome at 6 months is carbon monoxide verified continuous smoking abstinence. ETHICS AND DISSEMINATION: The trial was approved by the South Central-Oxford B Research Committee (21/SC/0288). Dissemination will include the publication of outcomes, and the process and economic evaluations in peer-reviewed journals. The findings will also be appropriately disseminated to relevant practice, policy and patient representative groups. TRIAL REGISTRATION NUMBER: NCT04854616; protocol V.4.2.

Indexed as

Electronic Nicotine Delivery SystemsSmoking CessationEnglandEquivalence Trials as TopicHumansMulticenter Studies as TopicPragmatic Clinical Trials as TopicRandomized Controlled Trials as TopicSmokingState Medicineaccident & emergency medicinepreventive medicinepublic health

Identifiers

PMID36657751
PMCPMC9853266

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.