Evidence map›Paper›PMID 36657670›Full record

ArticleThe Science of the total environment2023

Juxtaposition of intensive agriculture, vulnerable aquifers, and mixed chemical/microbial exposures in private-well tapwater in northeast Iowa.

Paul M Bradley, Dana W Kolpin, Darrin A Thompson, Kristin M Romanok, Kelly L Smalling, Sara E Breitmeyer, Mary C Cardon, David M Cwiertny, Nicola Evans, R William Field and 17 more

Open access · hybridAbstract read
In one paragraph

Article in The Science of the total environment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 4 institutions in 1 country.

Paul M BradleyU.S. Geological Survey, Columbia, SC, USA. Electronic address: pbradley@usgs.gov.
Dana W KolpinU.S. Geological Survey, Iowa City, IA, USA.
Darrin A ThompsonUniversity of Iowa, Iowa City, IA, USA.
Kristin M RomanokU.S. Geological Survey, Lawrenceville, NJ, USA.
Kelly L SmallingU.S. Geological Survey, Lawrenceville, NJ, USA.
Sara E BreitmeyerU.S. Geological Survey, Lawrenceville, NJ, USA.
Mary C CardonU.S. Environmental Protection Agency, Durham, NC, USA.
David M CwiertnyUniversity of Iowa, Iowa City, IA, USA.
Nicola EvansU.S. Environmental Protection Agency, Durham, NC, USA.
R William FieldUniversity of Iowa, Iowa City, IA, USA.
Michael J FocazioU.S. Geological Survey, Reston, VA, USA.
Laura E Beane FreemanNational Cancer Institute/NIH, Rockville, MD, USA.
Carrie E GivensU.S. Geological Survey, Lansing, MI, USA.
James L GrayU.S. Geological Survey, Lakewood, CO, USA.
Gordon L HagerNational Cancer Institute/NIH, Rockville, MD, USA.
Michelle L HladikU.S. Geological Survey, Sacramento, CA, USA.
Jonathan N HofmannNational Cancer Institute/NIH, Rockville, MD, USA.
Rena R JonesNational Cancer Institute/NIH, Rockville, MD, USA.
Leslie K KanagyU.S. Geological Survey, Lakewood, CO, USA.
Rachael F LaneU.S. Geological Survey, Lawrence, KS, USA.
R Blaine McCleskeyU.S. Geological Survey, Boulder, CO, USA.
Danielle MedgyesiNational Cancer Institute/NIH, Rockville, MD, USA.
Elizabeth K Medlock-KakaleyU.S. Environmental Protection Agency, Durham, NC, USA.
Shannon M MeppelinkU.S. Geological Survey, Iowa City, IA, USA.
Michael T MeyerU.S. Geological Survey, Lawrence, KS, USA.
Diana A StavrevaNational Cancer Institute/NIH, Rockville, MD, USA.
Mary H WardNational Cancer Institute/NIH, Rockville, MD, USA.
United States Geological Survey · USNational Cancer Institute · USEnvironmental Protection Agency · USUniversity of Iowa · US

Funding

Studies of Occupational Cancer (Pesticides)ZIACP010119 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI BEANE FREEMAN, LAURA · 2009 to 2025
$46.1M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5M
The Heartland Center for Occupational Health and Safety Education and Research CenterT42OH008491 · OH · UNIVERSITY OF IOWA · PI O'SHAUGHNESSY, PATRICK T · 2005 to 2025
$31.7M
In vivo Imaging Analysis of SteroidNuclear Receptor FunctionZIABC010308 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HAGER, GORDON L · 2009 to 2025
$8.4M
STUDIES OF OCCUPATIONAL CANCER--PESTICIDESZ01CP010119 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ALAVANJA, MICHAEL · 1996 to 2008
$5.0M
ACL HHS T42OH008491Intramural NIH HHS Z01 CP010119NIEHS NIH HHS P30 ES005605NIOSH CDC HHS T42 OH008491
6 · The paper itself

Abstract

In the United States and globally, contaminant exposure in unregulated private-well point-of-use tapwater (TW) is a recognized public-health data gap and an obstacle to both risk-management and homeowner decision making. To help address the lack of data on broad contaminant exposures in private-well TW from hydrologically-vulnerable (alluvial, karst) aquifers in agriculturally-intensive landscapes, samples were collected in 2018-2019 from 47 northeast Iowa farms and analyzed for 35 inorganics, 437 unique organics, 5 in vitro bioassays, and 11 microbial assays. Twenty-six inorganics and 51 organics, dominated by pesticides and related transformation products (35 herbicide-, 5 insecticide-, and 2 fungicide-related), were observed in TW. Heterotrophic bacteria detections were near ubiquitous (94 % of the samples), with detection of total coliform bacteria in 28 % of the samples and growth on at least one putative-pathogen selective media across all TW samples. Health-based hazard index screening levels were exceeded frequently in private-well TW and attributed primarily to inorganics (nitrate, uranium). Results support incorporation of residential treatment systems to protect against contaminant exposure and the need for increased monitoring of rural private-well homes. Continued assessment of unmonitored and unregulated private-supply TW is needed to model contaminant exposures and human-health risks.

Indexed as

Drinking WaterGroundwaterWater Pollutants, ChemicalAgricultureEnvironmental MonitoringHumansIowaUnited StatesDrinking WaterWater Pollutants, ChemicalAgricultural healthHuman healthInorganicsMicrobialOrganicsPrivate wellsTapwater contaminants

Identifiers

PMID36657670
PMCPMC9976626
OpenAlexW4316655638

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.