Evidence map›Paper›PMID 36657662›Full record

ArticleMucosal immunology2023

Tissue-resident memory T cells trigger rapid exudation and local antibody accumulation.

Pamela C Rosato, Sahar Lotfi-Emran, Vineet Joag, Sathi Wijeyesinghe, Clare F Quarnstrom, Hanna N Degefu, Rebecca Nedellec, Jason M Schenkel, Lalit K Beura, Lars Hangartner and 2 more

Abstract read
In one paragraph

Article in Mucosal immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. T-Cell Biology in the Female Reproductive Tract: Relevance to HIV Infection.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
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  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. CD8+ Tissue-Resident Memory T Cells: Versatile Guardians of the Tissue.Journal of immunology (Baltimore, Md. : 1950) · 2024
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Pamela C RosatoUniversity of Minnesota, Center for Immunology, Department of Microbiology and Immunology, Minneapolis, MN, USA; Geisel School of Medicine at Dartmouth College, Dartmouth Cancer Center, Department of Microbiology and Immunology, Lebanon, NH, USA.
Sahar Lotfi-EmranUniversity of Minnesota, Center for Immunology, Department of Microbiology and Immunology, Minneapolis, MN, USA.
Vineet JoagUniversity of Minnesota, Center for Immunology, Department of Microbiology and Immunology, Minneapolis, MN, USA.
Sathi WijeyesingheUniversity of Minnesota, Center for Immunology, Department of Microbiology and Immunology, Minneapolis, MN, USA.
Clare F QuarnstromUniversity of Minnesota, Center for Immunology, Department of Microbiology and Immunology, Minneapolis, MN, USA.
Hanna N DegefuGeisel School of Medicine at Dartmouth College, Dartmouth Cancer Center, Department of Microbiology and Immunology, Lebanon, NH, USA.
Rebecca NedellecDepartment of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.
Jason M SchenkelUniversity of Minnesota, Center for Immunology, Department of Microbiology and Immunology, Minneapolis, MN, USA.
Lalit K BeuraUniversity of Minnesota, Center for Immunology, Department of Microbiology and Immunology, Minneapolis, MN, USA; Brown University, Department of Molecular Microbiology and Immunology, Providence, RI, USA.
Lars HangartnerDepartment of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.
Dennis R BurtonDepartment of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
David MasopustUniversity of Minnesota, Center for Immunology, Department of Microbiology and Immunology, Minneapolis, MN, USA. Electronic address: masopust@umn.edu.

Funding

Identification of neutralizing epitopes on SARS-CoV-2 spike for design of vaccines and small-molecule antiviralsUM1AI144462 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI BURTON, DENNIS R. · 2019 to 2025
$201.6M
Understanding the role of RNA-binding protein mutations in cancerP20GM113132 · NIGMS · DARTMOUTH COLLEGE · PI LACEFIELD, SONI · 2016 to 2025
$25.9M
Mucosal T Cell Memory to PathogensR01AI084913 · NIAID · UNIVERSITY OF MINNESOTA · PI MASOPUST, DAVID · 2010 to 2023
$5.8M
Resident Memory T CellsR01AI146032 · NIAID · UNIVERSITY OF MINNESOTA · PI DAVID MASOPUST · 2020 to 2026
$3.8M
Function and regulation of brain resident memory T cellsK22AI148508 · NIAID · DARTMOUTH COLLEGE · PI ROSATO, PAMELA · 2021 to 2022
$269k
NIAID NIH HHS K22 AI148508NIAID NIH HHS R01 AI084913NIAID NIH HHS R01 AI146032NIAID NIH HHS UM1 AI144462NIGMS NIH HHS P20 GM113132
6 · The paper itself

Abstract

Adaptive immunity is didactically partitioned into humoral and cell-mediated effector mechanisms, which may imply that each arm is separate and does not function together. Here, we report that the activation of CD8+ resident memory T cells (T

Indexed as

CD8-Positive T-LymphocytesStomatitisAnimalsFemaleImmunoglobulinsImmunologic MemoryMemory T CellsMiceImmunoglobulins

Identifiers

PMID36657662
PMCPMC10338064

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.