ArticleThe American journal of medicine2023
Frailty Assessment and Perioperative Major Adverse Cardiovascular Events After Noncardiac Surgery.
Article in The American journal of medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 33 citations in OpenAlex.
- Performance of the AUB-HAS2 cardiovascular risk index in coronary artery disease: a multicenter retrospective cohort study.Annals of medicine · 2026Article
- The association between hospital frailty risk score and adverse inpatient outcomes in older adults with colorectal cancer.British journal of cancer · 2026Article
- Anesthesia for cataract surgery in Canada: deploying a limited workforce where it matters most.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026Article
- Heart Failure and Laparoscopic Cholecystectomy for Acute Cholecystitis: The Need for Frailty Assessment, Biomarkers, and MINS Surveillance.Clinical and translational gastroenterology · 2026Article
- Impact of anesthesia methods on adverse cardiovascular events during painless gastroscopy in frail older patients: study protocol for a prospective controlled trial.Frontiers in medicine · 2026Article
- Outcomes of patients with myeloproliferative neoplasms and critical limb ischemia: insights from the National readmissions database.Journal of thrombosis and thrombolysis · 2025Article
- Frailty and Cardiac Complications after Minor and Major Noncardiac Surgery in Older Adults.Anesthesiology · 2025Article
- Cardiac Troponin as a Prognostic Indicator for Major Adverse Cardiac Events in Non-Cardiac Surgery: A Narrative Review.Diagnostics (Basel, Switzerland) · 2025Review
- Major Adverse Cardiovascular Events and Cause-Specific Mortality After Hospitalisation in COPD.International journal of chronic obstructive pulmonary disease · 2025Article
- Geriatric nutritional risk index predicts perioperative cardiovascular events in older patients with coronary artery disease undergoing non-cardiac surgery: a multicenter retrospective cohort study.Frontiers in nutrition · 2025Article
- Modified Hospital Frailty Risk Score (mHFRS) as a Tool to Identify and Predict Outcomes for Hospitalised Older Adults at Risk of Frailty.Journal of frailty, sarcopenia and falls · 2024Article
- Risk of sarcopenia, frailty and malnutrition as predictors of postoperative delirium in surgery.BMC geriatrics · 2024Article
- The Impact of Frailty on Patients With AF and HFrEF Undergoing Catheter Ablation: A Nationwide Population Study.JACC. Advances · 2024Article
- Perioperative Mortality: A Retrospective Cohort Study of 75,446 Noncardiac Surgery Patients.Mayo Clinic proceedings. Innovations, quality & outcomes · 2024Article
- Predicting perioperative myocardial injury/infarction after noncardiac surgery in patients under surgical and medical co-management: a prospective cohort study.BMC geriatrics · 2024Article
- Automated Electronic Frailty Index-Identified Frailty Status and Associated Postsurgical Adverse Events.JAMA network open · 2023Article
- RAI-measured frailty predicts non-home discharge following metastatic brain tumor resection: national inpatient sample analysis of 20,185 patients.Journal of neuro-oncology · 2023Article
- The frail patient undergoing cardiac surgery: lessons learned and future perspectives.Frontiers in cardiovascular medicine · 2023Review
- Development and Internal Validation of a Nomogram for Predicting Postoperative Cardiac Events in Elderly Hip Fracture Patients.Clinical interventions in aging · 2023Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveFrailty is an emerging risk factor for adverse outcomes. However, perioperative frailty assessments derived from electronic health records have not been studied on a large scale. We aim to estimate the prevalence of frailty and the associated incidence of major adverse cardiovascular events (MACE) among adults hospitalized for noncardiac surgery.
methodsAdults aged ≥45 years hospitalized for noncardiac surgery from 2004-2014 were identified from the National Inpatient Sample. The validated Hospital Frailty Risk Score (HFRS) derived from International Classification of Diseases codes was used to classify patients as low (HFRS <5), medium (5-10), or high (>10) frailty risk. The primary outcome was MACE, defined as myocardial infarction, cardiac arrest, and in-hospital mortality. Multivariable logistic regression was used to estimate the adjusted odds of MACE stratified by age and HFRS.
resultsA total of 55,349,978 hospitalizations were identified, of which 81.0%, 14.4%, and 4.6% had low, medium, and high HFRS, respectively. Patients with higher HFRS had more cardiovascular risk factors and comorbidities. MACE occurred during 2.5% of surgical hospitalizations and was common among patients with high frailty scores (high HFRS: 9.1%, medium: 6.9%, low: 1.3%, P < .001). Medium (adjusted odds ratio [aOR] 2.05; 95% confidence interval [CI], 2.02-2.08) and high (aOR 2.75; 95% CI, 2.70-2.79) HFRS were associated with greater odds of MACE vs low HFRS, with the greatest odds of MACE observed in younger individuals 45-64 years (interaction P value < .001).
conclusionsThe HFRS may identify frail surgical inpatients at risk for adverse perioperative cardiovascular outcomes.
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