Evidence map›Paper›PMID 36657417›Full record

Trial reportOncology research and treatment2023

Effects of a Sound Intervention on Physical and Emotional Well-Being in Patients with Cancer: A Prospective Randomized Trial.

Anna Hohneck, Rosa Meissner, Christina Reyser, Lara Heinemann, Kathrin Christians, Kirsten Merx, Simone Weingärtner, Athanasios Mavratzas, Nadine Schulte, Iris Burkholder and 2 more

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Oncology research and treatment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Anna HohneckDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Rosa MeissnerDepartment of Hematology and Oncology, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany.
Christina ReyserDepartment of Hematology and Oncology, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany.
Lara HeinemannDepartment of Hematology and Oncology, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany.
Kathrin ChristiansQuerflötistin, Brückenstraße, Heidelberg, Germany.
Kirsten MerxDepartment of Hematology and Oncology, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany.
Simone WeingärtnerDepartment of Hematology and Oncology, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany.
Athanasios MavratzasDepartment of Hematology and Oncology, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany.
Nadine SchulteDepartment of Gastroenterology, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Iris BurkholderDepartment of Nursing and Health, University of Applied Sciences of the Saarland, Saarbruecken, Saarbrücken, Germany.
Wolf-Karsten HofmannDepartment of Hematology and Oncology, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany.
Ralf-Dieter HofheinzDepartment of Hematology and Oncology, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany.
Heidelberg University · DEHochschule für Technik und Wirtschaft des Saarlandes · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimCancer remains a disease with a significant impact on morbidity and mortality but also on quality of life. This prospective randomized pilot study investigated the effects of a sound intervention on physical and emotional well-being in outpatients with cancer.

methodsTwo self-applied sound interventions were used for this purpose, either active "music playing" with a body monochord or passive sound intervention with headphones to listen to a given music compilation. Interventions were carried out over a period of 4 weeks for at least 15 min in the evening before bedtime. The following self-assessment questionnaires were completed both at baseline and after 4 weeks to evaluate the response: the Pittsburgh Sleep Quality Index (PSQI), the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ-C30), Visual Analogue Scale (VAS) for pain and fatigue, and the Fear of Progression (FoP) questionnaire. Primary endpoint of this exploratory trial was to describe the rate of patients with improvement in at least one dimension without worsening of any other.

results73 patients (29 male, 44 female) were included in the study and randomized to either active (n = 34, 47%) or passive sound intervention (n = 39, 53%). Median age was 52.0 years (range 21-79). Fourteen patients (19%) stated that they were musically active. The sound intervention was carried out on a median of 26 days (range 5-28). A higher percentage of patients in the passive group reached the primary endpoint: n = 15 (39%) versus n = 9 (27%). Response differences in favour of the passive group were seen with the VAS fatigue and with QLQ-30 questionnaires. Overall, an improvement in QLQ-30 questionnaire was seen in 12 patients (31%) in the passive group versus 3 patients (9%). Moreover, sound intervention significantly improved social functioning and shortness of breath in the passive group according to QLQ-C30. Significant improvements were also noticed in the passive group in terms of affective reactions as a domain of the FoP questionnaire. No effects on pain or sleep quality could be observed.

conclusionA 4-week self-administered sound intervention was feasible in outpatients suffering from cancer. Using a panel of 5 questionnaires, passive sound interventions appeared to be more likely to positively influence patient-reported outcomes. In particular, a positive impact was documented in social functioning and fatigue.

Indexed as

NeoplasmsQuality of LifeAdultAgedFatigueFemaleHumansMaleMiddle AgedPainPilot ProjectsProspective StudiesSurveys and QuestionnairesYoung AdultActive music playingHeadphonesIntegrative cancer therapiesQuality of lifeSound intervention

Identifiers

PMID36657417
PMCPMC10015753
OpenAlexW4317567325

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.