Evidence map›Paper›PMID 36657396›Full record

ArticleNeuron2023

miR-124-3p mediates polygenic risk shared between schizophrenia and bipolar disorder.

Dariusz Żurawek, Gustavo Turecki

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Neuron, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Roles of AMPA receptors in social behaviors.Frontiers in synaptic neuroscience · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Dariusz ŻurawekDepartment of Psychiatry, Douglas Institute, McGill University, 6875 LaSalle Boulevard, Montreal, QC H4H 1R3, Canada.
Gustavo TureckiDepartment of Psychiatry, Douglas Institute, McGill University, 6875 LaSalle Boulevard, Montreal, QC H4H 1R3, Canada. Electronic address: gustavo.turecki@mcgill.ca.
Douglas Mental Health University Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of Neuron, Namkung et al. demonstrate that the microRNA miR-124-3p is associated with polygenic risk scores shared between schizophrenia and bipolar disorder and confers risk to behavioral alterations common to these two disorders through modulation of AMPA receptor neurotransmission.

Indexed as

Bipolar DisorderMicroRNAsSchizophreniaGenetic Predisposition to DiseaseHumansMultifactorial InheritanceRisk FactorsMicroRNAsMIRN124 microRNA, human

Identifiers

PMID36657396
OpenAlexW4317567936

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.