ArticleProceedings of the National Academy of Sciences of the United States of America2023
BAP1 is a novel regulator of HIF-1α.
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Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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0cells of the map it votes in
20citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
What it found
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Who cites it
20 citing papers in PubMed, 27 citations in OpenAlex.
- Research progress on the regulation of mesothelioma driven by deubiquitinating enzyme BAP1.Clinical and experimental medicine · 2026Review
- Epigenetic regulation of ACSL4 via H2A monoubiquitylation connects lipid metabolism to BAP1-mediated ferroptosis.Cell death and differentiation · 2026Article
- Essential genetic mutations impair DNA damage repair and modulate tumor immune microenvironment in ccRCC.MedScience · 2026Review
- BAP1 dysregulation impairs trophoblast differentiation and contributes to placental dysfunction in preeclampsia.Cell death & disease · 2026Article
- Single-cell epigenetic profiling reveals a tumor-intrinsic interferon response program in ccRCC tied to poor prognosis andScience advances · 2026Article
- Advances in the Basic Sciences in Thoracic Oncology in the Last 20 Years and Their Translational Impact.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2026Review
- Tumor suppressor BAP1 emerges as a key regulator of metabolism and cell death in tumors.Frontiers in cell and developmental biology · 2026Review
- USP13 promotes colorectal cancer progression by deubiquitinating and stabilizing HIF-1α.Cell communication and signaling : CCS · 2025Article
- Prospective Analysis of Mesotheliomas in Subjects With BAP1 Cancer Syndrome: Clinical Characteristics and Epigenetic Correlates of Disease.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2025Observational
- Pleural mesothelioma.Nature reviews. Disease primers · 2025Review
- Chromosomal 3p loss and 8q gain drive vasculogenic mimicry via HIF-2α and VE-cadherin activation in uveal melanoma.Cell death and differentiation · 2025Article
- YY1 enhances HIF-1α stability in tumor-associated macrophages to suppress anti-tumor immunity of prostate cancer in mice.Nature communications · 2025Article
- MYLIP attenuates hypoxia tolerance by inducing K27-linked polyubiquitination and subsequent proteasomal degradation of HIF-α.Communications biology · 2025Article
- Spring viremia of carp virus infection induces hypoxia response in zebrafish by stabilizing hif1α.Journal of virology · 2025Article
- The fall of the genome protectors triad: PBRM1, SETD2, and BAP1's impact on metabolism and immunity in clear cell renal cell carcinoma.Frontiers in cell and developmental biology · 2025Review
- Deubiquitinating enzyme mutagenesis screens identify a USP43-dependent HIF-1 transcriptional response.The EMBO journal · 2024Article
- Understanding the intersection between placental development and cancer: Lessons from the tumor suppressor BAP1.Communications biology · 2024Review
- USP38 promotes deubiquitination of K11-linked polyubiquitination of HIF1α at Lys769 to enhance hypoxia signaling.The Journal of biological chemistry · 2024Article
- Dysregulation of ubiquitination modification in renal cell carcinoma.Frontiers in genetics · 2024Review
- Preventive and therapeutic opportunities: targeting BAP1 and/or HMGB1 pathways to diminish the burden of mesothelioma.Journal of translational medicine · 2023Review
Corrections and comments
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Authors and funding
28 authors at 6 institutions in 3 countries.
Angela BononiThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.
Qian WangCenter for Theoretical Biological Physics, Rice University, Houston, TX 77005.
Alicia A ZolondickThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.
Fang BaiCenter for Theoretical Biological Physics, Rice University, Houston, TX 77005.ORCID 0000-0003-1468-5568
Mika Steele-TanjiThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.
Joelle S SuarezThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.ORCID 0000-0003-1528-2701
Sandra PastorinoThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.
Abigail SipesThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.
Valentina SignoratoThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.
Angelica FerroThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.
Flavia NovelliThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.ORCID 0000-0002-3746-7478
Jin-Hee KimThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.
Michael MinaaiThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.
Yasutaka TakinishiThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.
Laura PellegriniThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.
Andrea NapolitanoThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.
Ronghui XuThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.ORCID 0000-0002-9842-2628
Christine FarrarThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.ORCID 0000-0001-8561-2257
Chandra GoparajuThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.
Cristian BassiDepartment of Translational Medicine LTTA Centre University of Ferrara, Ferrara 44121, Italy.
Massimo NegriniDepartment of Translational Medicine LTTA Centre University of Ferrara, Ferrara 44121, Italy.
Ian PaganoThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.ORCID 0000-0002-6248-0113
Greg SakamotoThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.
Giovanni GaudinoThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.ORCID 0000-0002-1572-6571
Harvey I PassDepartment of Cardiothoracic Surgery, New York University, New York, NY 10016.
José N OnuchicCenter for Theoretical Biological Physics, Rice University, Houston, TX 77005.ORCID 0000-0002-9448-0388
Haining YangThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.ORCID 0000-0003-1417-2420
Michele CarboneThoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI 96813.ORCID 0000-0001-8928-8474
University of Hawaiʻi at Mānoa · USUniversity of Ferrara · ITCenter for Theoretical Biological Physics · USNew York University · USShanghaiTech University · CNUniversity of Science and Technology of China · CN
Funding
The EDRN Mesothelioma Biomarker Discovery LaboratoryU01CA214195 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PASS, HARVEY IRA, YANG, HAINING · 2016 to 2021
$3.5MMechanisms of BAP1 activity in human cancer developmentR01CA237235 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI CARBONE, MICHELE, YANG, HAINING · 2020 to 2024
$2.1MInfluence of germline mutations on susceptibility to environmental carcinogensR01ES030948 · NIEHS · UNIVERSITY OF HAWAII AT MANOA · PI CARBONE, MICHELE, GRZYMSKI, JOSEPH J · 2019 to 2021
$1.9MGermline BAP1 Mutations and Malignant Mesothelioma: Mechanisms and Early DetectionR01CA198138 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI CARBONE, MICHELE · 2015 to 2019
$1.7MLive-Cell Imaging System with TIRF and PhotomanipulationS10OD028515 · OD · UNIVERSITY OF HAWAII AT MANOA · PI FARRAR, CHRISTINE · 2020 to 2020
$382kNCI NIH HHS R01 CA198138NCI NIH HHS R01 CA237235NCI NIH HHS U01 CA214195NIEHS NIH HHS R01 ES030948NIH HHS S10 OD028515NIOSH CDC HHS U24 OH009077
Abstract
PubMed holds no abstract for this paper.
Indexed as
Hypoxia-Inducible Factor 1, alpha SubunitMesotheliomaMesothelioma, MalignantUbiquitin ThiolesteraseHeterozygoteHumansMutationTumor Suppressor ProteinsBAP1 protein, humanHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitTumor Suppressor ProteinsUbiquitin ThiolesteraseBAP1cancer syndromeHIF-1αhypoxiamesothelioma
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.