Evidence map›Paper›PMID 36656845›Full record

Observational studyPloS one2023

Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial.

Matthew J Meyer, Slater A Jameson, Edward J Gillig, Ankur Aggarwal, Sarah J Ratcliffe, Mary Baldwin, Karen E Singh, W Darrin Clouse, Randal S Blank

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04836702 (Vascular Surgery Outcomes), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04836702 completednot on this map

Vascular Surgery Outcomes: Echocardiography as Risk-Assessment for Major Adverse Cardiac Events in Major Vascular Surgery Patients

TypeobservationalSponsorUniversity of VirginiaRan2011 to 2022Enrolled813ConditionsLeft-Sided Heart Failure, Right-Sided Heart Failure, Heart Valve Diseases
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Matthew J MeyerDepartment of Anesthesiology, University of Virginia School of Medicine, Charlottesville, VA, United States of America.ORCID 0000-0003-4486-3214
Slater A JamesonDepartment of Anesthesiology, University of Virginia School of Medicine, Charlottesville, VA, United States of America.
Edward J GilligDepartment of Anesthesiology, Newton Wellesley Hospital, Newton, MA, United States of America.
Ankur AggarwalDepartment of Surgery, Franciscan Physicians Network Vascular Surgeons, Indianapolis, IN, United States of America.
Sarah J RatcliffeDepartment of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA, United States of America.
Mary BaldwinDepartment of Surgery, University of Virginia School of Medicine, Charlottesville, VA, United States of America.ORCID 0000-0003-2275-1596
Karen E SinghDepartment of Anesthesiology, University of Virginia School of Medicine, Charlottesville, VA, United States of America.
W Darrin ClouseDepartment of Surgery, University of Virginia School of Medicine, Charlottesville, VA, United States of America.
Randal S BlankDepartment of Anesthesiology, University of Virginia School of Medicine, Charlottesville, VA, United States of America.
University of Virginia · USFranciscan Health Indianapolis · USNewton Wellesley Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPeripheral artery disease and cardiac disease are often comorbid conditions. Echocardiography is a diagnostic tool that can be performed preoperatively to risk stratify patients by a functional cardiac test. We hypothesized that ventricular dysfunction and valvular lesions were associated with an increased incidence of expanded major adverse cardiac events (Expanded MACE). METHODS AND MATERIALS: Retrospective cohort study from 2011 to 2020 including all patients from a major academic center who had vascular surgery and an echocardiographic study within two years of the index procedure.

results813 patients were included in the study; a majority had a history of smoking (86%), an ASA score of 3 (65%), and were male (68%). Carotid endarterectomy was the most common surgery (24%) and the least common surgery was open abdominal aortic aneurysm repair (5%). We found no significant association between the echocardiographic findings of left ventricular dysfunction, right ventricular dysfunction, or valvular lesions and the postoperative development of Expanded MACE.

conclusionsThe preoperative echocardiographic findings of left ventricular dysfunction, right ventricular dysfunction and moderate to severe valvular lesions were not predictive of an increased incidence of postoperative Expanded MACE. We identified a significant association between RV dysfunction and post-operative dialysis that should be interpreted carefully due to the small number of outcomes. The transition from open to endovascular surgery and advances in perioperative management may have led to improved cardiovascular outcomes.

trial registrationTrial Registration: NCT04836702 (clinicaltrials.gov). https://www.google.com/search?client=firefox-b-d&q=NCT04836702.

Indexed as

Cardiovascular SystemVentricular Dysfunction, LeftVentricular Dysfunction, RightEchocardiographyFemaleHumansMaleRetrospective StudiesVascular Surgical Procedures

Identifiers

PMID36656845
PMCPMC9851553
OpenAlexW4317438809

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.