Evidence map›Paper›PMID 36656752›Full record

ArticleeLife2023

Gasotransmitter modulation of hypoglossal motoneuron activity.

Brigitte M Browe, Ying-Jie Peng, Jayasri Nanduri, Nanduri R Prabhakar, Alfredo J Garcia

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Brigitte M BroweInstitute for Integrative Physiology, University of Chicago, Chicago, United States.ORCID 0000-0003-1282-2290
Ying-Jie PengInstitute for Integrative Physiology, University of Chicago, Chicago, United States.
Jayasri NanduriInstitute for Integrative Physiology, University of Chicago, Chicago, United States.
Nanduri R PrabhakarInstitute for Integrative Physiology, University of Chicago, Chicago, United States.
Alfredo J GarciaInstitute for Integrative Physiology, University of Chicago, Chicago, United States.ORCID 0000-0001-5620-7519
University of Chicago · US

Funding

Mechanisms Underlying Sympathetic Activation-dependent Endothelial Cell Activation by Chronic Intermittent HypoxiaP01HL144454 · NHLBI · UNIVERSITY OF CHICAGO · PI PRABHAKAR, NANDURI R · 2019 to 2023
$12.7M
Mechanisms of repeated opioid use dependent remodeling in respiratory controlR01HL163965 · NHLBI · UNIVERSITY OF CHICAGO · PI GARCIA, ALFREDO J, OTERO, JOSE JAVIER · 2022 to 2025
$3.0M
Neurocognitive Consequences of Intermittent HypoxiaR01NS107421 · NINDS · UNIVERSITY OF CHICAGO · PI GARCIA, ALFREDO J · 2018 to 2022
$2.3M
CRCNS: Evidence-based modeling of neuromodulatory action on network propertiesR01DA057767 · NIDA · UNIVERSITY OF IOWA · PI Yangyang Wang · 2022 to 2026
$1.8M
NHLBI NIH HHS P01 HL144454NHLBI NIH HHS R01 HL163965NHLBI NIH HHS R01HL163965NIDA NIH HHS R01 DA057767NIDA NIH HHS R01DA057767NINDS NIH HHS R01 NS107421NINDS NIH HHS R01NS107421
6 · The paper itself

Abstract

Obstructive sleep apnea (OSA) is characterized by sporadic collapse of the upper airway leading to periodic disruptions in breathing. Upper airway patency is governed by genioglossal nerve activity that originates from the hypoglossal motor nucleus. Mice with targeted deletion of the gene

Indexed as

GasotransmittersSleep Apnea, ObstructiveAnimalsHypoglossal NerveMedulla OblongataMiceMotor NeuronsRespirationGasotransmitterscarbon monoxidehydrogen sulfidemotoneuronmouseneurosciencesleep apneaupper airway

Identifiers

PMID36656752
PMCPMC9977277
OpenAlexW4317480512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.