Evidence map›Paper›PMID 36656331›Full record

SynthesisWorld journal of urology2023

Assessment of single-probe dual-energy lithotripters in percutaneous nephrolithotomy: a systematic review and meta-analysis of preclinical and clinical studies.

Ioannis Mykoniatis, Nikolaos Pyrgidis, Lazaros Tzelves, Amelia Pietropaolo, Patrick Juliebø-Jones, Vincent De Coninck, Belthangady M Zeeshan Hameed, Michael Chaloupka, Gerald Bastian Schulz, Christian Stief and 3 more

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Innovations in Kidney Stone Removal.Research and reports in urology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 7 countries.

Ioannis MykoniatisFirst Department of Urology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Nikolaos PyrgidisDepartment of Urology, University Hospital, LMU Munich, Munich-Marchioninistr. 15, 81377, Munich, Germany.
Lazaros TzelvesSecond Department of Urology, Sismanoglio Hospital, Sismanogliou 37, Athens, Greece.
Amelia PietropaoloDepartment of Urology, University of Hospital Southampton NHS Trust, Southampton, UK.
Patrick Juliebø-JonesDepartment of Urology, Haukeland University Hospital, Bergen, Norway.
Vincent De ConinckDepartment of Urology, AZ Klina, Brasschaat, Belgium.
Belthangady M Zeeshan HameedDepartment of Urology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, India.
Michael ChaloupkaDepartment of Urology, University Hospital, LMU Munich, Munich-Marchioninistr. 15, 81377, Munich, Germany.
Gerald Bastian SchulzDepartment of Urology, University Hospital, LMU Munich, Munich-Marchioninistr. 15, 81377, Munich, Germany.
Christian StiefDepartment of Urology, University Hospital, LMU Munich, Munich-Marchioninistr. 15, 81377, Munich, Germany.
Panagiotis KallidonisDepartment of Urology, University of Patras, Patras, Greece.
Bhaskar K SomaniDepartment of Urology, University of Hospital Southampton NHS Trust, Southampton, UK.
Andreas SkolarikosSecond Department of Urology, Sismanoglio Hospital, Sismanogliou 37, Athens, Greece. andskol@yahoo.com.
European Association of Urology · NLLMU Klinikum · DELudwig-Maximilians-Universität München · DEUniversity Hospital Southampton NHS Foundation Trust · GBAristotle University of Thessaloniki · GRKasturba Medical College, Manipal · INSismanoglio General Hospital · GRUniversity College London Hospitals NHS Foundation Trust · GBUniversity of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the safety and efficacy of single-probe dual-energy (SPDE) lithotripters in patients undergoing percutaneous nephrolithotripsy (PCNL) through a systematic review and meta-analysis.

methodsWe searched PubMed, Cochrane Library, Scopus and Embase databases until July 2022 for any preclinical or clinical studies, exploring the safety and efficacy of different SPDE lithotripters in patients undergoing PCNL. We performed a meta-analysis to compare stone-free rate, bleeding, or other complications and mean operative time between SPDE lithotripters and other lithotripters (PROSPERO: CRD42021285631).

resultsWe included 16 studies (six preclinical, seven observational and three randomized with 625 participants) in the systematic review and four in the meta-analysis. Preclinical studies suggest that SPDE lithotripters are safe and effective for the management of renal stones. Among clinical studies, four studies assessed Trilogy with no comparative arm, two compared Trilogy or ShockPulse with a dual-probe dual-energy lithotripter, two compared Trilogy with a laser, one compared ShockPulse with a pneumatic lithotripter, and one directly compared Trilogy with ShockPulse. Comparing SPDE lithotripters to other lithotripters, no significant differences were demonstrated in stone free rate (OR 1.13, 95% CI 0.53-2.38, I

conclusionsSPDE lithotripters represent a promising treatment modality for patients requiring PCNL. Despite the initial encouraging findings of preclinical and isolated clinical studies, it seems that Trilogy or ShockPulse provide similar efficiency compared to older generation devices.

Indexed as

Kidney CalculiLithotripsyNephrolithotomy, PercutaneousNephrostomy, PercutaneousHumansOperative TimePostoperative ComplicationsTreatment OutcomeMeta-analysisPercutaneous nephrolithotripsyRenal stonesSingle-probe dual-energy lithotriptersSystematic review

Identifiers

PMID36656331
OpenAlexW4317436125

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.