Evidence map›Paper›PMID 36655920›Full record

ArticleJournal of global health2023

Associations of the COVID-19 pandemic with quality of life: A cross-sectional study of older-age people with and without HIV in rural Uganda.

Brianne Olivieri-Mui, Susanne S Hoeppner, Yao Tong, Emma Kohrt, Lien T Quach, Deanna Saylor, Janet Seeley, Alexander C Tsai, Zahra Reynolds, Samson Okello and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of global health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 11 institutions in 3 countries.

Brianne Olivieri-MuiDepartment of Health Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, USA.
Susanne S HoeppnerCollege of Science and Mathematics, University of Massachusetts Boston, Boston, USA.
Yao TongMedical Practice Evaluation Center, Mongan Institute, Department of Medicine, Massachusetts General Hospital, Boston, USA.
Emma KohrtDepartment of Health Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, USA.
Lien T QuachMedical Practice Evaluation Center, Mongan Institute, Department of Medicine, Massachusetts General Hospital, Boston, USA.
Deanna SaylorDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, USA.
Janet SeeleyDepartment of Global Health and Development, Faculty of Public Health and Policy, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Alexander C TsaiHarvard Medical School, Boston, USA.
Zahra ReynoldsMedical Practice Evaluation Center, Mongan Institute, Department of Medicine, Massachusetts General Hospital, Boston, USA.
Samson OkelloGillings School of Global Public Health, University of North Carolina, Chapel Hill, USA.
Stephen AsiimweMedical Practice Evaluation Center, Mongan Institute, Department of Medicine, Massachusetts General Hospital, Boston, USA.
Atwiine FlaviaMbarara University of Science and Technology.
Ruth SentongoMbarara University of Science and Technology.
Edna TindimwebwaKabwohe Clinical Research Centre, Kabwohe Town, Uganda.
Ana-Claire MeyerDenali Therapeutics, Inc., South San Francisco, California, USA.
Noeline NakasujjaDepartment of Psychiatry, College of Health Sciences, Makerere University, Kampala, Uganda.
Robert PaulDepartment of Psychological Sciences, University of Missouri-St Louis, St. Louis, USA.
Christine RitchieHarvard Medical School, Boston, USA.
Meredith GreeneDivision of Geriatrics, Department of Medicine, University of California at San Francisco, San Francisco, USA.
Mark J SiednerHarvard Medical School, Boston, USA.
Massachusetts General Hospital · USMbarara University of Science and Technology · UGHarvard University · USNortheastern University · USBoston University · USDenali Therapeutics (United States) · USFaculty of Public Health · GBJohns Hopkins University · USMakerere University · UGUniversity of California, San Francisco · USUniversity of Missouri–St. Louis · US

Funding

Quality of Life and Aging with HIV in Rural UgandaR01AG059504 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI SIEDNER, MARK J · 2019 to 2023
$3.4M
Social Networks, HIV Stigma, and the HIV Care Cascade in Rural UgandaR01MH113494 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI TSAI, ALEXANDER C · 2017 to 2021
$3.2M
Epidemiology of coronary artery disease among people with HIV in rural sub-Saharan AfricaR01HL141053 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI SIEDNER, MARK J · 2018 to 2021
$3.0M
Mentoring patient-oriented research to improve cardiovascular health among people with HIV in sub-Saharan AfricaK24HL166024 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI MARK J SIEDNER · 2022 to 2026
$616k
Polycyclic aromatic hydrocarbons exposure and dietary risk of Esophageal squamous cell carcinoma in UgandaK43TW010715 · FIC · MBARARA UNIVERSITY/SCIENCE/ TECHNOLOGY · PI OKELLO, SAMSON · 2017 to 2021
$456k
FIC NIH HHS K43 TW010715NHLBI NIH HHS K24 HL166024NHLBI NIH HHS R01 HL141053NIA NIH HHS R01 AG059504NIMH NIH HHS R01 MH113494
6 · The paper itself

Abstract

Background: COVID-19-related lockdowns and other public health measures may have differentially affected the quality of life (QOL) of older people with and without human immunodeficiency virus (HIV) in rural Uganda. Methods: The Quality of Life and Aging with HIV in Rural Uganda study enrolled people with and without HIV aged over 49 from October 2020 to October 2021. We collected data on COVID-19-related stressors (behavior changes, concerns, interruptions in health care, income, and food) and the participants' QOL. We used linear regression to estimate the associations between COVID-19-related stressors and QOL, adjusting for demographic characteristics, mental and physical health, and time before vs after the lockdown during the second COVID-19 wave in Uganda. Interaction between HIV and COVID-19-related stressors evaluated effect modification. Results: We analyzed complete data from 562 participants. Mean age was 58 (standard deviation (SD) = 7); 265 (47%) participants were female, 386 (69%) were married, 279 (50%) had HIV, and 400 (71%) were farmers. Those making ≥5 COVID-19-related behavior changes compared to those making ≤2 had worse general QOL (estimated linear regression coefficient (b) = - 4.77; 95% confidence interval (CI) = -6.61, -2.94) and health-related QOL (b = -4.60; 95% CI = -8.69, -0.51). Having access to sufficient food after the start of the COVID-19 pandemic (b = 3.10, 95% CI = 1.54, 4.66) and being interviewed after the start of the second lockdown (b = 2.79, 95% CI = 1.30, 4.28) were associated with better general QOL. Having HIV was associated with better health-related QOL (b = 5.67, 95% CI = 2.91,8.42). HIV was not associated with, nor did it modify the association of COVID-19-related stressors with general QOL. Conclusions: In the context of the COVID-19 pandemic in an HIV-endemic, low-resource setting, there was reduced QOL among older Ugandans making multiple COVID-19 related behavioral changes. Nonetheless, good QOL during the second COVID-19 wave may suggest resilience among older Ugandans.

Indexed as

COVID-19HIV InfectionsAgedCommunicable Disease ControlCross-Sectional StudiesFemaleHIVHumansMaleMiddle AgedPandemicsQuality of LifeUganda

Identifiers

PMID36655920
PMCPMC9850875
OpenAlexW4317435321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.