Evidence map›Paper›PMID 36655710›Full record

ReviewLab on a chip2023

Conformational-switch biosensors as novel tools to support continuous, real-time molecular monitoring in lab-on-a-chip devices.

Claudio Parolo, Andrea Idili, Jason Heikenfeld, Kevin W Plaxco

Abstract readReview
In one paragraph

Review in Lab on a chip, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Claudio ParoloBarcelona Institute for Global Health, Hospital Clínic Universitat de Barcelona, 08036, Barcelona, Spain.ORCID 0000-0001-9481-4408
Andrea IdiliDepartment of Chemical Science and Technologies, University of Rome, Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-6004-270X
Jason HeikenfeldNovel Devices Laboratory, University of Cincinnati, Cincinnati, Ohio, USA.
Kevin W PlaxcoDepartment of Chemistry and Biochemistry, University of California Santa Barbara, Santa Barbara, California, USA. kwp@ucsb.edu.ORCID 0000-0003-4772-8771

Funding

Bio-electrochemical detectors for in vivo continuous monitoringR01EB022015 · NIBIB · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI KIPPIN, TOD EDWARD, PLAXCO, KEVIN W · 2017 to 2025
$4.6M
NIBIB NIH HHS R01 EB022015
6 · The paper itself

Abstract

Recent years have seen continued expansion of the functionality of lab on a chip (LOC) devices. Indeed LOCs now provide scientists and developers with useful and versatile platforms across a myriad of chemical and biological applications. The field still fails, however, to integrate an often important element of bench-top analytics: real-time molecular measurements that can be used to "guide" a chemical response. Here we describe the analytical techniques that could provide LOCs with such real-time molecular monitoring capabilities. It appears to us that, among the approaches that are general (

Indexed as

Biosensing TechniquesMicrofluidic Analytical TechniquesLab-On-A-Chip Devices

Identifiers

PMID36655710
PMCPMC10799767

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.