Evidence map›Paper›PMID 36655619›Full record

ArticleJournal of applied clinical medical physics2023

Dosimetric accuracy of the Convolution algorithm for Leksell Gamma Plan radiosurgery treatment planning: Evaluation in the presence of clinically relevant inhomogeneities.

Evaggelos Pantelis, Andreas Logothetis, Emmanouil Zoros, Eleftherios P Pappas, Panagiotis Papagiannis, Ian Paddick, Håkan Nordström, George Kollias, Pantelis Karaiskos

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Article in Journal of applied clinical medical physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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5 citing papers in PubMed.

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5 · Who and what money

Authors and funding

9 authors.

Evaggelos PantelisMedical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Andreas LogothetisMedical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Emmanouil ZorosMedical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Eleftherios P PappasMedical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Panagiotis PapagiannisMedical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Ian PaddickMedical Genesis Care Centre for Radiotherapy, Cromwell Hospital, London, UK.
Håkan NordströmElekta Instrument AB, Stockholm, Sweden.
George KolliasDepartments of Medical Physics and Gamma Knife, Hygeia Hospital, Athens, Greece.
Pantelis KaraiskosMedical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Funding

This work was supported by Elekta AB
6 · The paper itself

Abstract

purposeThe Leksell Gamma Plan Convolution algorithm (LGP-Convolution) has not been widely adopted. This mainly stems from the higher calculated beam-on times relative to the standard ray tracing-based LGP-TMR10 dose calculation algorithm. This study aims to evaluate the accuracy of the LGP-Convolution in scenarios where the treated lesions are in the vicinity of or encompassed by bone and/or air inhomogeneities.

methodsThe solid water dosimetry phantom provided by the vendor was modified to include bone and air inhomogeneities. Two treatment planning scenarios were investigated involving a single shot and multiple shots, respectively. Treatment planning and dose prescription were performed using the LGP-Convolution algorithm. Triple channel film dosimetry was performed using GafChromic EBT3 films calibrated in terms of absorbed dose to water in a RESULTS AND

conclusionsEBT3 dose to medium correction factors ranged with field size (4, 8, or 16 mm) within 0.941-0.946 for bone and 0.745-0.749 for air inhomogeneities. An excellent agreement was found between the LGP-Convolution calculations with corresponding EBT3 and MC dose to medium results at all measurement points, except those located inside the air inhomogeneity. The latter is of no clinical importance and excluding them yielded gamma index passing rates of nearly 100% for 3% local dose difference and 1 mm distance-to-agreement criteria. The excellent agreement observed between LGP-Convolution calculations and film as well as MC results of dose to medium indicates that the latter is the quantity reported by the LGP-Convolution.

Indexed as

RadiosurgeryAlgorithmsHumansMonte Carlo MethodPhantoms, ImagingRadiotherapy DosageRadiotherapy Planning, Computer-AssistedWaterWaterbone inhomogeneitydose calculation accuracydose to mediumGamma Plan ConvolutionLeksell Gamma Knife

Identifiers

PMID36655619
PMCPMC10161100

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